DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and prss60.1

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	264	Identity:	104/264 - (39%)
Similarity:	150/264 - (56%)	Gaps:	30/264 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   787 VCGRRMFP-EPRIVGGANAAFGRWPWQISLRQWRTSTY-LHKCGAALLNENWAITAAHCVDNVPP 849
            |||  :.| ..|||||.||..|.||||:||   .:..| .|.||.:|:|..|.:|||||:..:..
Zfish    24 VCG--LAPLNNRIVGGVNAFDGSWPWQVSL---HSPIYGGHFCGGSLINSEWVLTAAHCLPRITT 83

  Fly   850 SDLLLRLGEYDLAEEEEPYGYQ-ERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCV 913
            |.||:.||:   ..::....|: .|.|.::..||.::..|.|.|:|||.....|.|...|.|||:
Zfish    84 SSLLVFLGK---TTQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSAVTFSNYIRPVCL 145

  Fly   914 PDNDENF-IGQTAFVTGWG--RLYEDGPLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFIC 975
            ...:..| .|.::::||||  :|..:.|.|.:|||..:||:.|..|.::..|..    :.:..||
Zfish   146 AAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGSGS----VTNNMIC 206

  Fly   976 AGWKKGGYDSCEGDSGGPMVLQR-----ESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWI 1035
            ||..:||.|:|:||||||||.::     :|       |:.|||.|||:...||||||:|:::.||
Zfish   207 AGLLQGGRDTCQGDSGGPMVSKQCLVWVQS-------GITSWGYGCADPYSPGVYTRVSQYQSWI 264

  Fly  1036 NQIL 1039
            |.|:
Zfish   265 NSII 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	96/247 (39%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	98/249 (39%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	96/247 (39%)
		Tryp_SPc	34..267	CDD:238113	98/249 (39%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810