DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and st14b

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	351	Identity:	123/351 - (35%)
Similarity:	179/351 - (50%)	Gaps:	44/351 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   706 KTTEAPASS---IELASSTSSYTDL--GSDLAASSSSSTTTTTSSPTTAAETTDYSGEEPNTTTI 765
            ||.|....|   |......:.|.|.  |||.:..:.|          .|...:|.:.:..|...|
Zfish   537 KTWEFRCRSGRCISAQKQCNGYNDCGDGSDESRCAKS----------IAVHCSDSTYKCKNKQCI 591

  Fly   766 EATGSTTVAPANALEGVDYKEV-CGRRMFPEPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGA 829
            ...........:.::|.|..|. ||::.....|||||.::..|.||||:||..   .|..|.|||
Zfish   592 SKLNPMCDGETDCVDGSDEAECKCGKKPHKSSRIVGGKDSDEGEWPWQVSLHM---KTQGHVCGA 653

  Fly   830 ALLNENWAITAAHCVDNVPPSDLLLRLGEYDLAEEEEPY-GYQ---------ERRVQIVASHPQF 884
            ::::.:|.:||||||.:   :|..    .|..|::.|.| |..         :|.|..:..|||:
Zfish   654 SVISNSWLVTAAHCVQD---NDQF----RYSQADQWEVYLGLHNQGETSKSTQRSVLRIIPHPQY 711

  Fly   885 DPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENF-IGQTAFVTGWGRLYE-DGPLPSVLQEVA 947
            |..:::.|:||:....||....||.|:|:||....| .|::.::||||:|.| ...:|||||:..
Zfish   712 DHSSYDNDIALMELDSPVTLNQNIWPICLPDPTHYFPAGKSVWITGWGKLREGSDAVPSVLQKAE 776

  Fly   948 VPVINNTICESMYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISW 1012
            |.:||:|:|..:....    ..||: ||||...||.|:|:||||||| ...|.:.|..|.||:||
Zfish   777 VRIINSTVCSKLMDDG----ITPHM-ICAGVLSGGVDACQGDSGGPM-SSIEGNGRMFLAGVVSW 835

  Fly  1013 GIGCAEANQPGVYTRISEFRDWINQI 1038
            |.||...|:||||||::::|.||.:|
Zfish   836 GDGCGRRNRPGVYTRVTDYRSWIREI 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	100/249 (40%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	101/251 (40%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060	10/32 (31%)
		LDLa	578..613	CDD:238060	5/34 (15%)
		Tryp_SPc	624..858	CDD:214473	100/249 (40%)
		Tryp_SPc	625..861	CDD:238113	101/251 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	188	1.000	Domainoid score	I3236
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810