Protein Alignment Np and PRSS22

DIOPT Version :10

• Sequence 1: NP_610437.2
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 128/431 - (29%)
• Similarity: 199/431 - (46%)
• Gaps: 71/431 - (16%)

  Fly   645 KTSASTAPPSATDKVVISVATSVSEVETHGPGKPQKTTKPPKPSSTAKPTTTTTAAAT--TIVKT 707
            ||....:.|.:...|.:::|.|:|               ||     ..|.::::||..  :.|..
Human     4 KTQQVRSAPRSPVTVGVAIACSLS---------------PP-----CSPISSSSAACLWGSTVLC 48

  Fly   708 TEAPASSIELASSTSSYTDLGSDLAASSSSSTTTT-TSSPTTAAETTDYS--------------G 757
            ......|.| .:|.||....|:.:.||........ ..:...||....:|              |
Human    49 CSCRRRSGE-GTSGSSVQSRGAQVCASLEEPVLVPGRQAGREAAGGQGHSCAARAWPGPRKCPAG 112

  Fly   758 EEPNTTTIE-------ATGSTTVAPANALEGVDYKEVCGRRMFPEP--RIVGGANAAFGRWPWQI 813
            ..|....:|       |.||:..|..||.. :.....||:   |:.  |:|||.::....|||.:
Human   113 RGPGVERLESLPGHWRARGSSPPAILNAAR-IPVPPACGK---PQQLNRVVGGEDSTDSEWPWIV 173

  Fly   814 SLRQWRTSTYLHKCGAALLNENWAITAAHCV-DNV-PPSDLLLRLGEYDLAEEEEPYGYQERRVQ 876
            |:::..|    |.|..:||...|.||||||. ||: .|....:.||.:.|...    |.:.::|.
Human   174 SIQKNGT----HHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNP----GSRSQKVG 230

  Fly   877 I--VASHPQFDPRTFE-YDLALLRFYEPVIFQPNIIPVCVPDNDENFIGQT-AFVTGWGRLYEDG 937
            :  |..||.:..:... .|:||:|....:.|...::|:|:||...:....| .:::|||.:.:..
Human   231 VAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGV 295

  Fly   938 PL--PSVLQEVAVPVINNTICESMY-RSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQRE 999
            ||  |..||::.||:|::.:|..:| |.||. ..|....:|||:.:|..|:|.||||||::.|
Human   296 PLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQ-GPITEDMLCAGYLEGERDACLGDSGGPLMCQ-- 357

  Fly  1000 SDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQILQ 1040
            .|..:.|.|:||||.||||.|:||||..:|..|.|:.:|:|
Human   358 VDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQ 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_610437.2	Tryp_SPc	798..1038	CDD:238113	89/248 (36%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	89/248 (36%)