Protein Alignment Np and PRSS2

DIOPT Version :10

• Sequence 1: NP_610437.2
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 82/258 - (31%)
• Similarity: 129/258 - (50%)
• Gaps: 34/258 - (13%)

  Fly   795 EPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDL------- 852
            :.:||||........|:|:||    .|.| |.||.:|::|.|.::|.||..:...|.|
Human    21 DDKIVGGYICEENSVPYQVSL----NSGY-HFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEY 80

  Fly   853 ---LLRLGEY--DLAEEEEPYGYQERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVC 912
               .:||||:  ::.|..|.:....:    :..||:::.||.:.|:.|::...|.:....:..:.
Human    81 HRIQVRLGEHNIEVLEGNEQFINAAK----IIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAIS 141

  Fly   913 VPDNDENFIGQTAFVTGWGRLYEDG-PLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICA 976
            :| ......|..:.::|||.....| ..|..||.:..||::...||     |.|...|.:...|.
Human   142 LP-TAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECE-----ASYPGKITNNMFCV 200

  Fly   977 GWKKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQIL 1039
            |:.:||.|||:||||||:|...|      |.|::|||.|||:.|:|||||::..:.|||...:
Human   201 GFLEGGKDSCQGDSGGPVVSNGE------LQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_610437.2	Tryp_SPc	798..1038	CDD:238113	82/252 (33%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	82/252 (33%)