Protein Alignment Np and PRSS1

DIOPT Version :10

• Sequence 1: NP_610437.2
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 82/248 - (33%)
• Similarity: 124/248 - (50%)
• Gaps: 28/248 - (11%)

  Fly   795 EPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDLLLRLGEY 859
            :.:||||.|......|:|:||    .|.| |.||.:|:||.|.::|.||.    .|.:.:||||:
Human    21 DDKIVGGYNCEENSVPYQVSL----NSGY-HFCGGSLINEQWVVSAGHCY----KSRIQVRLGEH 76

  Fly   860 --DLAEEEEPYGYQERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENFIG 922
              ::.|..|.:....:    :..|||:|.:|...|:.|::.....:....:..:.:| ......|
Human    77 NIEVLEGNEQFINAAK----IIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLP-TAPPATG 136

  Fly   923 QTAFVTGWGRLYEDG-PLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAGWKKGGYDSC 986
            ....::|||.....| ..|..||.:..||::...||     |.|...|.....|.|:.:||.|||
Human   137 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCE-----ASYPGKITSNMFCVGFLEGGKDSC 196

  Fly   987 EGDSGGPMVLQRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQIL 1039
            :||||||:|...:      |.||:|||.|||:.|:|||||::..:..||...:
Human   197 QGDSGGPVVCNGQ------LQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_610437.2	Tryp_SPc	798..1038	CDD:238113	82/242 (34%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	80/240 (33%)