Protein Alignment Np and KLK15

DIOPT Version :10

• Sequence 1: NP_610437.2
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 76/260 - (29%)
• Similarity: 130/260 - (50%)
• Gaps: 42/260 - (16%)

  Fly   797 RIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDLLLRLGEYDL 861
            :::.|...|....|||::|  :....:  .|||:|::.:|.::||||....    :.:||||::|
Human    21 KLLEGDECAPHSQPWQVAL--YERGRF--NCGASLISPHWVLSAAHCQSRF----MRVRLGEHNL 77

  Fly   862 AEEEEPYGYQERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENFIGQTAF 926
            .:.:.|  .|.|....|..||:::.|:...|:.|||..:|....|.:.|..:|....: .|:...
Human    78 RKRDGP--EQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPH-PGEACV 139

  Fly   927 VTGWGRLYEDGP-----------LPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAGWKK 980
            |:|||.:..:.|           ||..|....:.:|::|.|:..|..     .:.:..:|||.:.
Human   140 VSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPG-----RLTNTMVCAGAEG 199

  Fly   981 GGYDSCEGDSGGPMV----LQRESDKRFHLGGVISWG-IGCAEANQPGVYTRISEFRDWINQILQ 1040
            .|.:|||||||||:|    ||          |::||| :.|....:|||||::..:.:||.:.::
Human   200 RGAESCEGDSGGPLVCGGILQ----------GIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMK 254

  Fly  1041  1040
            Human   255  254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_610437.2	Tryp_SPc	798..1038	CDD:238113	76/255 (30%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	74/249 (30%)