Protein Alignment Np and Tmprss2

DIOPT Version :9

• Sequence 1: NP_001246213.1
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 490
• Identity: 142/490 - (28%)
• Similarity: 201/490 - (41%)
• Gaps: 101/490 - (20%)

  Fly   614 PPTNASISN----DWQPAPPSNWLPLTTESSETADKTSASTAPPSATDKVVISVATSVSEVETHG 674
            ||...:..|    .:.|:|...:.|..|        |.|||                 |.:.||.
Mouse    30 PPVAPNGYNLYPAQYYPSPVPQYAPRIT--------TQAST-----------------SVIHTHP 69

  Fly   675 PGKPQKTTKPPKPS---STAKPTTTTTAAATTIV---------KTTEAPASSIELASSTSSYTD- 726
            .......|...|.|   :.|..|..|.||...::         .|:|....|.....|:|.:.|
Mouse    70 KSSGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDG 134

  Fly   727 -----LGSD-------------LAASSSS--------STTTTTSSPTTAAETTDYSGEEPNTTTI 765
                 .|.|             |...||.        ....:.|....|.:...|.....::..|
Mouse   135 VAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGI 199

  Fly   766 -EATGSTTVAPANALEG-VD-YKEV------------------CG-RRMFPEPRIVGGANAAFGR 808
             :.:|:|:....|...| || ||::                  || |.:..:.|||||.||:.|.
Mouse   200 PDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVKRQSRIVGGLNASPGD 264

  Fly   809 WPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDLLLRLGEYDLAEEEEPYGYQER 873
            ||||:||.    ...:|.||.:::...|.:||||||:....|..........|.:....|| ...
Mouse   265 WPWQVSLH----VQGVHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYG-SRH 324

  Fly   874 RVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENF-IGQTAFVTGWGRLYEDG 937
            :|:.|.|||.:|.:|...|:||::...|:.|...:.|||:|:..... :.|..:::|||..||.|
Mouse   325 QVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKG 389

  Fly   938 PLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQRESDK 1002
            ....||....||:|..:.|.|.|.   |...|....||||:.:|..|||:||||||:|..:..
Mouse   390 KTSDVLNAAMVPLIEPSKCNSKYI---YNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNG-- 449

  Fly  1003 RFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQ 1037
            .:.|.|..|||.|||:|.:||||..::.|.|||.|
Mouse   450 IWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQ 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	91/238 (38%)
		Tryp_SPc	798..1038	CDD:238113	93/241 (39%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060	8/34 (24%)
		SRCR_2	152..247	CDD:373897	17/94 (18%)
		Tryp_SPc	254..485	CDD:238113	93/241 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3257
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8807
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810