DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and CG1299

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	129/414 - (31%)
Similarity:	186/414 - (44%)	Gaps:	57/414 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   668 SEVETHGPGKPQKTTKPPKPSSTAKPTTTTTAAATT---IVKTTEA----------------PAS 713
            ||....||..|.:.  |..|.....|.||||...||   |..|:.|                |.:
  Fly   111 SESTFIGPQPPPEV--PDNPFLIPTPRTTTTTTTTTPAPIPDTSAAPLIEPRGTVCRGPDTKPGN 173

  Fly   714 SIELASSTSSYTDLGSDLAASSSSSTTTTTSSPTTAAETTDYSGEEPNTTTIEATGSTTVAPANA 778
            .:|:....|...:|      .|.|...|..:....:.......|.:....|.:...:||.||:..
  Fly   174 CVEIKECASLLNEL------RSRSQDATFANFLRASNAVCQNKGTQVCCPTGQGITNTTPAPSQI 232

  Fly   779 LEG---------VDYKEVCGRRMFPEPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNE 834
            :..         ::.:|.||..:....:||||..:..|.|||...|.....|....|||..|:..
  Fly   233 VPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITA 297

  Fly   835 NWAITAAHCVDNVPPSDL-LLRLGEYDLAEEEEPYGYQERRVQIVASHPQFDPRTFEYDLALLRF 898
            ...:|||||:    ..|| .:||||:||:.:.|. |:.:..:....|||.::.|....|:|:|..
  Fly   298 RHVLTAAHCI----RQDLQFVRLGEHDLSTDTET-GHVDINIARYVSHPDYNRRNGRSDMAILYL 357

  Fly   899 YEPVIFQPNIIPVCVPD----NDENFIGQTAFVTGWGRLYEDGPLPSVLQEVAVPVINNTIC--- 956
            ...|.|...|.|:|:|.    ..::::|...||.|||:..|.|....||.|:.:|:.:|.:|
  Fly   358 ERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQS 422

  Fly   957 ---ESMYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQR--ESDKRFHLGGVISWGIGC 1016
               |..|.||   :......:|||...||.|:|:||||||::|..  :...||:|.||:|:||||
  Fly   423 YAKEKRYFSA---DQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGC 484

  Fly  1017 AEANQPGVYTRISEFRDWINQILQ 1040
            |..|.||||:....|.|||.|.:|
  Fly   485 ARPNVPGVYSSTQYFMDWIIQQVQ 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	92/250 (37%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	94/252 (37%)
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	8/57 (14%)
		Tryp_SPc	260..503	CDD:214473	92/250 (37%)
		Tryp_SPc	261..503	CDD:238113	92/249 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	3.010