DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	106/375 - (28%)
Similarity:	171/375 - (45%)	Gaps:	50/375 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   675 PGKPQKTTKPPKPSSTAK--PTTTTTAAATTIVKTTEAPASSIELASSTSSYTDLGSDLAASSSS 737
            |.||..|.:..|..||.:  .....|.|:......|||.|.:   |.....|         :|..
  Rat   138 PEKPGVTVRLSKDRSTLQVLDAARGTWASVCFDNFTEALAKT---ACRQMGY---------NSQP 190

  Fly   738 STTTTTSSPTTAAETTDYSGEEPNTTTIEATGSTTVAPANALEGVDYKEVCGRRMFPEPRIVGGA 802
            :.......|......|..:|..........:.|.......:|..:|    ||:.: ...|:|||.
  Rat   191 AFGPVEMGPNQTLLVTPVTGNSQELQMQNGSRSCLSGSLVSLRCLD----CGKSL-KTTRVVGGV 250

  Fly   803 NAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDN-VPPSDLLLRLGEYDLAEEEE 866
            .|:...||||:|::..:.    |.||.::|:.:|.:|||||... :..|...:|.|...|.....
  Rat   251 EASADSWPWQVSIQYNKQ----HVCGGSILDHHWILTAAHCFRKYLDVSSWKVRAGSNKLGNSPS 311

  Fly   867 -PYGYQERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENFI-GQTAFVTG 929
             |..    ::.|...:| ..|:  |.|:||::...|:.|..::.|:|:|.:||..| ....:|.|
  Rat   312 LPVA----KIFIAEPNP-LQPK--EKDIALVKLKMPLTFSGSVRPICLPFSDEELIPTMPVWVIG 369

  Fly   930 WGRLYED-GPLPSVLQEVAVPVINNTIC--ESMYR---SAGYIEHIPHIFICAGWKKGGYDSCEG 988
            ||...|: |.:...|.:.:|.||::..|  |..|:   :||        .:|||..:||.|:|:|
  Rat   370 WGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAG--------MLCAGTPQGGKDTCQG 426

  Fly   989 DSGGPMVLQRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQI 1038
            |||||::...:   ::.:.|::|||.||...:.|||||:::.:.|||..:
  Rat   427 DSGGPLMYHYD---KWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWIYNV 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	80/246 (33%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	81/248 (33%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	18/104 (17%)
		Tryp_SPc	245..470	CDD:214473	80/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910