DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and CG8170

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_610441.2	Gene:	CG8170 / 35908	FlyBaseID:	FBgn0033365	Length:	855	Species:	Drosophila melanogaster

Alignment Length:	926	Identity:	225/926 - (24%)
Similarity:	329/926 - (35%)	Gaps:	270/926 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 THQQETTTTTTRRHTRPTGSSSVASRTTS-------KTTTTTTTTTTTTAA--------PPTTTS 352
            |.:..|.|||..|.||.|...|..:...|       .::..|.||:.||||        |..|.:
  Fly     5 TDENNTNTTTASRSTRNTWRWSRLALAVSLFAYCCCASSAATPTTSVTTAALLSGHQLLPWQTAA 69

  Fly   353 TRAATTTQRPTPPLRTTTSKPHKTHSSRRPAPAKKPVSTTTTTASGTQSTRKPADSLASGSTTAN 417
            ..|||     ||........||::.|.......|              ..|:.:|
  Fly    70 ATAAT-----TPSTARNLYAPHQSFSRHDDISFK--------------DLRQRSD---------- 105

  Fly   418 GTTATTLPARRPVTQTSSSSTTTTSTTSTITTTVFKD--ELPKNRTTT-------RLPERTTQAP 473
            ||...:..:.|...|....|||....:......:...  |||:....|       .:||..|:..
  Fly   106 GTVVQSFGSYRTARQFGGYSTTAQRRSDPAVEIIPAPSVELPQGELITVPKQLVPTMPENVTRQG 170

  Fly   474 RPR-----PKPT-GEIVKVPALLAEPTTTTVTKGSSSSSSSSPKPPASSTTPLVTKKKPTTTNAP 532
            |.|     |..| ||......|...|        |.:::.|:..|||.....:          |.
  Fly   171 RRRNYMYIPLQTEGENGSAALLQLRP--------SRNATLSALGPPADGVAAV----------AH 217

  Fly   533 TTTTTTTTTTTTTTTPKPTRRTKPPTTTTTTTTKATTTTTK---ATTTTTTAK-----PLITTEP 589
            .......|..:....|.......|..|..:....|.::|.|   |....|:.:     |..:.:|
  Fly   218 EFGADLATQGSGPEQPPLALELGPERTERSDLMAAASSTDKLEYAEPENTSRRVGFQFPSYSLKP 282

  Fly   590 PT---------SAPLTTTTKKTGLITWTDVEAEPPTNASISNDWQPAPPSNWLPLTTESSET--- 642
            .:         ..|:...|...|      .|.:|     .|.|..|.||    |...|..||
  Fly   283 ASPFHPQAYREDNPIFGDTSAGG------YEPQP-----YSEDASPVPP----PTQYEQHETRHT 332

  Fly   643 ------ADKTSASTAPPSATD-------KVVISVATSVSEVETHGP------GKPQK-------- 680
                  :|..|:|...|....       |:.....|...::  :||      .:||:
  Fly   333 RQLYFDSDTASSSFEFPGLVSNSKPHGLKLYRDDVTKFGDI--NGPITALPQQRPQRGFYFGDTE 395

  Fly   681 -TTKPPKP------------------------------SSTAKPTT---TTTAAATTIVKTTEAP 711
             .|.||.|                              .|:..|..   |.....||   ....|
  Fly   396 FRTGPPAPVRQFGPQKNFQEYVGPSEYQGTRKSRYYPYKSSRSPRVVFPTNDNVGTT---GPSGP 457

  Fly   712 ASSI-----------------------ELASSTSSYTDLGSDLAASSSSSTTTTTSSPTTAAE-- 751
            |.|.                       |||    :..|:.:|.:.....|.:..||||.:|:.
  Fly   458 AGSSGPSGNGVYFSDNIAFRDQNFGINELA----AVQDVRNDYSLQDLDSASEATSSPQSASTFK 518

  Fly   752 -----TTDYSGEEPNTT------------TIEAT------------------GST---------T 772
                 |||...:....|            .|:.|                  ||:         |
  Fly   519 EKVDITTDTECQHRGGTCEFFLGCWLSGGLIQGTCDGLLRGCCHRTAKSANLGSSDFVGNAVDLT 583

  Fly   773 VAPANALEGVDYKEVCG---RRMFPEPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNE 834
            ..|......|:.:..||   .:...:.|||||.:|.||.:|||..:|...:     :||.:|::.
  Fly   584 DLPQKNYGPVNNEPSCGISLAKQTAQRRIVGGDDAGFGSFPWQAYIRIGSS-----RCGGSLISR 643

  Fly   835 NWAITAAHCVDNVPPSDLLLRLGEYDLAEEEEP---YGYQERRVQIVASHP--QFDPRTFEYDLA 894
            ...:||.|||....|..:.:.||:|.:....||   |.:..||:.:   ||  :|.|:...:|::
  Fly   644 RHVVTAGHCVARATPRQVHVTLGDYVINSAVEPLPAYTFGVRRIDV---HPYFKFTPQADRFDIS 705

  Fly   895 LLRFYEPVIFQPNIIPVCVPDNDENFIGQTAFVTGWGRLYEDGPL-PSVLQEVAVPVINNTICES 958
            :|.....|.|.|:|.|:|:|:.:|:|:|:..:..|||.|.....| |..||.|.||||.|.|||.
  Fly   706 VLTLERTVHFMPHIAPICLPEKNEDFLGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICER 770

  Fly   959 MYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISWGIGCAEANQPG 1023
            .:|..|....|....:|||::.||.|||:||||||  |..:.:.|::|.||:|.|..||...|||
  Fly   771 WHRQNGINVVIYQEMLCAGYRNGGKDSCQGDSGGP--LMHDKNGRWYLIGVVSAGYSCASRGQPG 833

  Fly  1024 VYTRISEFRDWINQIL 1039
            :|..:|:..||::.::
  Fly   834 IYHSVSKTVDWVSYVV 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	94/243 (39%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	94/245 (38%)
CG8170	NP_610441.2	Tryp_SPc	611..845	CDD:214473	94/243 (39%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	94/243 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010