DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Np and prss60.3

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	263	Identity:	97/263 - (36%)
Similarity:	141/263 - (53%)	Gaps:	34/263 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   787 VCGRRMFPEPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSD 851
            |||:... ..|||||.||:.|.||||:||...:...  |.||.:|::..|.:|||||:..|..:.
Zfish    26 VCGQAPL-NTRIVGGVNASPGSWPWQVSLHSPKYGG--HFCGGSLISSEWVLTAAHCLSGVSETT 87

  Fly   852 LLLRLGEYDLAEEEEPYGYQERRVQIVAS--HPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCV- 913
            |::.||.    ..::.....|....:..|  |..::..|.:.|:||||....|.|...|.|||:
Zfish    88 LVVYLGR----RTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCLA 148

  Fly   914 PDNDENFIGQTAFVTGWGRLYEDG---PLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFIC 975
            ..|.....|.::::||||.: :.|   |.|.:|||..:||:.|..|.::..|.    .:.:..||
Zfish   149 AQNSVYSAGTSSWITGWGDI-QAGVNLPAPGILQETMIPVVANDRCNALLGSG----TVTNNMIC 208

  Fly   976 AGWKKGGYDSCEGDSGGPMV-------LQRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRD 1033
            ||..:||.|:|:||||||||       :|         .|:.|||.|||:.|.||||||:|:::.
Zfish   209 AGLTQGGKDTCQGDSGGPMVTRLCTVWVQ---------AGITSWGYGCADPNSPGVYTRVSQYQS 264

  Fly  1034 WIN 1036
            ||:
Zfish   265 WIS 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	92/250 (37%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	93/252 (37%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	93/252 (37%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900