DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	105/257 - (40%)
Similarity:	151/257 - (58%)	Gaps:	18/257 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   788 CGRRMFPEPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCV-DNVPPSD 851
            ||.|....||||||..::..:||||:|| |::.   .|.||.:::...|.:|||||| |...|..
  Rat   207 CGMRTGYSPRIVGGNVSSLTQWPWQVSL-QFQG---YHLCGGSVITPLWIVTAAHCVYDLYHPKS 267

  Fly   852 LLLRLGEYDLAEEEEPYGYQERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDN 916
            ..:::|...|.:...|    ...|:.:..|.::.|:....|:||::..||:.|...|.|:|:|::
  Rat   268 WTVQVGLVSLMDSPVP----SHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNS 328

  Fly   917 DENF-IGQTAFVTGWGRLYED--GPLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAGW 978
            :||| .|:..:.:|||.. ||  |....||...|||:|:|.||.......|.|.  |.: :|||:
  Rat   329 EENFPDGKLCWTSGWGAT-EDGAGDASPVLNHAAVPLISNKICNHRDVYGGIIS--PSM-LCAGY 389

  Fly   979 KKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQILQ 1040
            .|||.|||:||||||:|.|..  :.:.|.|..|:||||||.|:|||||||:.|.|||::.|:
  Rat   390 LKGGVDSCQGDSGGPLVCQER--RLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLE 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	98/241 (41%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	99/243 (41%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	2/3 (67%)
		Tryp_SPc	216..444	CDD:214473	98/241 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9079
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810