DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and mst1

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	323	Identity:	87/323 - (26%)
Similarity:	135/323 - (41%)	Gaps:	75/323 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   743 TSSPTTAAETTDY------SGEEPNTTTIEATGSTTVAPANALEGVDYKEVCGR---RMFPEPRI 798
            ||.|.|   ..||      :||:     :...|.||        .|::.| ||:   |:....||
Zfish   435 TSDPKT---EFDYCAIKQCAGEK-----VPIIGPTT--------EVEFNE-CGKREDRLRSRLRI 482

  Fly   799 VGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHC-----VDNVPPSDLLLRL-- 856
            |||..   |..||.:|||..:.:   |.||.:|::..|.|:...|     ||....:.::..|
Zfish   483 VGGTP---GNSPWTVSLRDRKGN---HFCGGSLVSSEWVISTKQCFSSCYVDLTGYTAMMGTLFR 541

  Fly   857 ----GEYDLAEEEEPYGYQERRVQI--VASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPD 915
                ||.||           :|:.:  :...|.      |..|.:|:...|..|...:..:|:|
Zfish   542 DPKEGEPDL-----------QRISLTKIVCGPS------ESHLVMLQLETPAQFNERVSQICLP- 588

  Fly   916 NDENFI---GQTAFVTGWGRLYEDGPLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAG 977
             .|.:|   |....:.|||.....|. .:||....:||::|..|...::.     .:....:|..
Zfish   589 -PERYIVPDGTICEIAGWGETKGKGD-ETVLNVAQMPVLSNKDCNQYFKG-----RVRENEMCTM 646

  Fly   978 WKKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQILQ 1040
            ..:.|..:||.|.|||:..| .|| .:.|.|||.....|..|.||.::.|:|.:.|||.::::
Zfish   647 AFQAGVGACERDYGGPLACQ-NSD-CWVLEGVIIPMRRCGHAGQPNIFIRVSVYVDWIKKVME 707

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	69/253 (27%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	70/255 (27%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056	6/18 (33%)
		Tryp_SPc	481..702	CDD:214473	69/253 (27%)
		Tryp_SPc	482..705	CDD:238113	70/255 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I4203
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.050