Protein Alignment Np and KLK5

DIOPT Version :10

• Sequence 1: NP_610437.2
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 93/293 - (31%)
• Similarity: 130/293 - (44%)
• Gaps: 40/293 - (13%)

  Fly   754 DYSGEEPNTTTIEATGSTTVAPANALEGVDYKEVCGRRMFPEPRIVGGANAAFGRWPWQISLRQW 818
            |.|.:.|:.|.  .:||.....|.|  |.|     .|......||:.|::......|||.:|...
Human    32 DVSCDHPSNTV--PSGSNQDLGAGA--GED-----ARSDDSSSRIINGSDCDMHTQPWQAALLLR 87

  Fly   819 RTSTYLHKCGAALLNENWAITAAHCVDNVPPSDLLLRLGEYDLAEEEEPYGYQERRVQIVAS--H 881
            ....|   |||.|::..|.:|||||...|    ..:|||.|.|:   ..|...::..|.|.|  |
Human    88 PNQLY---CGAVLVHPQWLLTAAHCRKKV----FRVRLGHYSLS---PVYESGQQMFQGVKSIPH 142

  Fly   882 PQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDNDENFIGQTAFVTGWGRLYEDGP---LPSVL 943
            |.:.......||.|::....:....::.|:.|..:..: .|....|:|||.  ...|   .|.||
Human   143 PGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS-AGTKCLVSGWGT--TKSPQVHFPKVL 204

  Fly   944 QEVAVPVINNTICESMYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQRESDKRFHLGG 1008
            |.:.:.|::...||.     .|...|.....||| .|.|.|||:||||||:|....      |.|
Human   205 QCLNISVLSQKRCED-----AYPRQIDDTMFCAG-DKAGRDSCQGDSGGPVVCNGS------LQG 257

  Fly  1009 VISWG-IGCAEANQPGVYTRISEFRDWINQILQ 1040
            ::||| ..||..|:|||||.:.:|..||.:.:|
Human   258 LVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_610437.2	Tryp_SPc	798..1038	CDD:238113	80/245 (33%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		10/39 (26%)
		Tryp_SPc	66..285	CDD:214473	79/243 (33%)