DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and Klkb1

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	106/298 - (35%)
Similarity:	162/298 - (54%)	Gaps:	32/298 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   752 TTDYSGEEPNTTTIEATGST--TVAPANALEGVDYKEVCGRRMFPEPRIVGGANAAFGRWPWQIS 814
            :||.|   |...|.||.||:  ::.....:|..|    |..::  ..|||||.|::.|.||||:|
  Rat   352 STDGS---PTRITYEAQGSSGYSLRLCKVVESSD----CTTKI--NARIVGGTNSSLGEWPWQVS 407

  Fly   815 LRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDL------LLRLGEYDLAEEEEPYGYQER 873
            | |.:..:..|.||.:::...|.:|||||.|.:|..|:      :|.|.|   ...:.|:.
  Rat   408 L-QVKLVSQNHMCGGSIIGRQWILTAAHCFDGIPYPDVWRIYGGILNLSE---ITNKTPFS---- 464

  Fly   874 RVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDN-DENFIGQTAFVTGWGRLYEDG 937
            .::.:..|.::......||:||::...|:.:.....|:|:|.. |.|.|....:|||||...|.|
  Rat   465 SIKELIIHQKYKMSEGSYDIALIKLQTPLNYTEFQKPICLPSKADTNTIYTNCWVTGWGYTKERG 529

  Fly   938 PLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQRESDK 1002
            ...::||:..:|::.|..|:..||.  |:  |....||||:|:||.|:|:||||||:|.:...
  Rat   530 ETQNILQKATIPLVPNEECQKKYRD--YV--ITKQMICAGYKEGGIDACKGDSGGPLVCKHSG-- 588

  Fly  1003 RFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQILQ 1040
            |:.|.|:.|||.|||...||||||:::|:.|||.:.:|
  Rat   589 RWQLVGITSWGEGCARKEQPGVYTKVAEYIDWILEKIQ 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	91/244 (37%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	92/246 (37%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	9/25 (36%)
		Tryp_SPc	390..621	CDD:214473	91/244 (37%)
		Tryp_SPc	391..621	CDD:238113	90/243 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9079
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810