Protein Alignment Np and F10

DIOPT Version :10

• Sequence 1: NP_610437.2
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 96/304 - (31%)
• Similarity: 158/304 - (51%)
• Gaps: 30/304 - (9%)

  Fly   748 TAAETTDYSGEEPNTTTIEATGSTTVAPA-NALEGVDYKEVCGRRMFPE------PRIVGGANAA 805
            :.|:.|..|||.|::.|.:...:..:.|. |..:.:|:.:.     .||      .|||||....
Human   183 SVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQT-----QPERGDNNLTRIVGGQECK 242

  Fly   806 FGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVPPSDLLLRLGEYDLAEEEEPYGY 870
            .|..|||..|.......:   ||..:|:|.:.:|||||:  .......:|:|  |...|:|..|.
Human   243 DGECPWQALLINEENEGF---CGGTILSEFYILTAAHCL--YQAKRFKVRVG--DRNTEQEEGGE 300

  Fly   871 QERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDND--ENFI--GQTAFVTGWG 931
            ....|::|..|.:|...|:::|:|:||...|:.|:.|:.|.|:|:.|  |:.:  .:|..|:|:|
Human   301 AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFG 365

  Fly   932 RLYEDGPLPSVLQEVAVPVINNTICESMYRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVL 996
            |.:|.|...:.|:.:.||.::...|:   .|:.:|  |.....|||:.....|:|:||||||.|
Human   366 RTHEKGRQSTRLKMLEVPYVDRNSCK---LSSSFI--ITQNMFCAGYDTKQEDACQGDSGGPHV- 424

  Fly   997 QRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWINQILQ 1040
            .|..|..| :.|::|||.|||...:.|:||:::.|..||::.::
Human   425 TRFKDTYF-VTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_610437.2	Tryp_SPc	798..1038	CDD:238113	83/243 (34%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203		7/19 (37%)
		Tryp_SPc	235..464	CDD:238113	83/242 (34%)
		O-glycosylated at one site	476..485