DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Np and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001246213.1	Gene:	Np / 35904	FlyBaseID:	FBgn0265011	Length:	1041	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	257	Identity:	95/257 - (36%)
Similarity:	139/257 - (54%)	Gaps:	27/257 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   788 CGRRMFPEPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAITAAHCVDNVP-PSD 851
            ||.|.....|||||..:|.|::|||:||.....    |.||.:::...|.:||||||..:. |..
Zfish   288 CGSRPKFSARIVGGNLSAEGQFPWQVSLHFQNE----HLCGGSIITSRWILTAAHCVYGIAYPMY 348

  Fly   852 LLLRLGEYDLAEEEEPYGYQERRVQIVASHPQFDPRTFEYDLALLRFYEPVIFQPNIIPVCVPDN 916
            .::..|..:|...    ..:...|:.:..|.::.|:..::|:||::..:|:.|...:.|:|:|:.
Zfish   349 WMVYAGLTELPLN----AVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLPNF 409

  Fly   917 DENF-IGQTAFVTGWGRLYEDGPLPSVLQEVA-VPVINNTICESM-----YRSAGYIEHIPHIFI 974
            .|.| .|:..:::|||.. |||...||.|..| ||:|:|..|...     |.:||        .|
Zfish   410 GEQFEDGKMCWISGWGAT-EDGGDASVSQHCASVPLISNKACSQPEVYQGYLTAG--------MI 465

  Fly   975 CAGWKKGGYDSCEGDSGGPMVLQRESDKRFHLGGVISWGIGCAEANQPGVYTRISEFRDWIN 1036
            |||:..||.|||:||||||:..  |....:.|.|..|||.||||.|:|||||||::...||:
Zfish   466 CAGYLDGGTDSCQGDSGGPLAC--EDSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWIH 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	90/245 (37%)
Np	NP_001246213.1	Tryp_SPc	798..1038	CDD:238113	91/247 (37%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	2/3 (67%)
		Tryp_SPc	298..525	CDD:238113	90/245 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810