DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and prss60.1

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	269	Identity:	96/269 - (35%)
Similarity:	143/269 - (53%)	Gaps:	31/269 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1432 HSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHC 1496
            ||....||:.|  .:.|||||..:..|::||||.:....:.|.|    |||.||.|.:|:|||||
Zfish    19 HSQLNVCGLAP--LNNRIVGGVNAFDGSWPWQVSLHSPIYGGHF----CGGSLINSEWVLTAAHC 77

  Fly  1497 QPGF-LASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHI 1560
            .|.. .:||:..:|:....|  .:...:.:.|..:.||..|:..|.|||:|||.|.|.|.|..:|
Zfish    78 LPRITTSSLLVFLGKTTQQG--VNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSAVTFSNYI 140

  Fly  1561 VPICMPNDVADF-TGRMATVTGWGRLKYGGGVPS--VLQEVQVPIIENSVCQEMFHTAGHNKKIL 1622
            .|:|:....:.| .|..:.:||||.::.|..:|:  :|||..:|::.|..|..:..:.    .:.
Zfish   141 RPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGSG----SVT 201

  Fly  1623 TSFLCAGYANGQKDSCEGDSGGPLV-------LQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTT 1680
            .:.:|||...|.:|:|:||||||:|       :|        :|..|.|..||.||.||||.|.:
Zfish   202 NNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQ--------SGITSWGYGCADPYSPGVYTRVS 258

  Fly  1681 FYKPWLRSI 1689
            .|:.|:.||
Zfish   259 QYQSWINSI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	88/250 (35%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	88/248 (35%)
		Tryp_SPc	34..267	CDD:238113	88/250 (35%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910