DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and Prss22

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	XP_006524968.4	Gene:	Prss22 / 70835	MGIID:	1918085	Length:	365	Species:	Mus musculus

Alignment Length:	274	Identity:	89/274 - (32%)
Similarity:	143/274 - (52%)	Gaps:	33/274 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1435 STECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHC--- 1496
            |.:|| :|. :..|||||:.|....:||.|.:.::      ..:.|.|.|:|:|:|:|||||
Mouse    96 SPDCG-KPQ-QLNRIVGGEDSMDAQWPWIVSILKN------GSHHCAGSLLTNRWVVTAAHCFKS 152

  Fly  1497 ---QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYD-PATFENDLALLELDSPVQFD 1557
               :|...:.|   :|.:.:..  ...||....:..|:.|.:|. ......|:||:.|:..:||.
Mouse   153 NMDKPSLFSVL---LGAWKLGS--PGPRSQKVGIAWVLPHPRYSWKEGTHADIALVRLEHSIQFS 212

  Fly  1558 THIVPICMPNDVADFTGRM-----ATVTGWGRLKYGGGV--PSVLQEVQVPIIENSVCQEMFHTA 1615
            ..|:|||:|    |.:.|:     ..:.|||.::.|..:  |..||:::||||::.:|:.::...
Mouse   213 ERILPICLP----DSSVRLPPKTDCWIAGWGSIQDGVPLPHPQTLQKLKVPIIDSELCKSLYWRG 273

  Fly  1616 GHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTT 1680
            ...:.|....|||||..|::|:|.|||||||:.| .|..:.|.|.:|.|..||....||||....
Mouse   274 AGQEAITEGMLCAGYLEGERDACLGDSGGPLMCQ-VDDHWLLTGIISWGEGCAERNRPGVYTSLL 337

  Fly  1681 FYKPWL-RSITGVK 1693
            .::.|: |.:.||:
Mouse   338 AHRSWVQRIVQGVQ 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	82/254 (32%)
Prss22	XP_006524968.4	Tryp_SPc	108..346	CDD:238113	81/253 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I3858
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910