DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and CG18735

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	95/250 - (38%)
Similarity:	132/250 - (52%)	Gaps:	23/250 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1448 RIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHCQPGFLASLVAVMGEFD 1512
            |||||:.:....|||.:::   .|.|.|   .||..|:..:|.:|||||..||...|:.|.
  Fly    82 RIVGGQETEVHEYPWMIML---MWFGNF---YCGASLVNDQYALTAAHCVNGFYHRLITVR---- 136

  Fly  1513 ISGDLESKRS------VTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVAD 1571
               .||..|.      |.:.|.||::|.:|....|::|:||:..:.||:....:.|:|||....:
  Fly   137 ---LLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSEN 198

  Fly  1572 FTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYA-NGQK 1635
            :.|:.|.|||||.|..||.:...||||:|||:....|:...:   ...||..:.:||||. .|.|
  Fly   199 YAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNY---GESKITDNMICAGYVEQGGK 260

  Fly  1636 DSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWLRSIT 1690
            |||:||||||:.:......|:|||.||.|..||.|..||||.|...:..|:...|
  Fly   261 DSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	93/246 (38%)
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	93/244 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	93/246 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457814
Domainoid	1	1.000	147	1.000	Domainoid score	I2768
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840