DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and hpn

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001091657.2	Gene:	hpn / 569259	ZFINID:	ZDB-GENE-141212-373	Length:	425	Species:	Danio rerio

Alignment Length:	265	Identity:	101/265 - (38%)
Similarity:	145/265 - (54%)	Gaps:	29/265 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly  1437 ECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHCQP--- 1498
            :|| |..:...|||||..:..|::||||.::   :.|:   ::|||.:|:.|::|:||||.|
Zfish   153 DCG-RRMLPEERIVGGVDARQGSWPWQVSLQ---YDGV---HQCGGSIISDRWIISAAHCFPERY 210

  Fly  1499 GFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFEN------DLALLELDSPVQFD 1557
            ...:....:||  .|......|..|...||.|:.|..|.|....|      |:|::.|..|:||.
Zfish   211 RHASRWRVLMG--SIYNTPIRKNVVIAEVKTVVYHSSYLPFVDANIDDNSRDIAVISLTKPLQFT 273

  Fly  1558 THIVPICMP---NDVADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNK 1619
            .:|.|:|:|   ..:||  |:|.||||||.::|.|...:||||..||||.::||....:   ::.
Zfish   274 DYIQPVCLPTYGQRLAD--GQMGTVTGWGNVEYYGTQANVLQEAHVPIISDAVCNGPDY---YDN 333

  Fly  1620 KILTSFLCAGYANGQKDSCEGDSGGPLV---LQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTF 1681
            ::.|:..||||..|..|||:||||||.|   :.....||.|.|.||.|..||....||||.|.:.
Zfish   334 QVTTTMFCAGYEKGGTDSCQGDSGGPFVAADVLSKTSRYRLLGVVSWGTGCAMAKKPGVYTRVSR 398

  Fly  1682 YKPWL 1686
            :.||:
Zfish   399 FLPWI 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	97/253 (38%)
hpn	NP_001091657.2	SRCR_2	54..160	CDD:321960	3/7 (43%)
hpn	NP_001091657.2	Tryp_SPc	164..404	CDD:238113	97/253 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910