Protein Alignment flz and KLK7

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 84/278 - (30%)
• Similarity: 126/278 - (45%)
• Gaps: 46/278 - (16%)

  Fly  1421 SRTLPTP------NLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNK 1479
            :|:|..|      :||..:...|      .:..:|:.|.....|::||||.:.....|      .
Human     2 ARSLLLPLQILLLSLALETAGEE------AQGDKIIDGAPCARGSHPWQVALLSGNQL------H 54

  Fly  1480 CGGVLITSRYVITAAHCQPGFLASLVAVMGEFDI---SGDLESKRSVTKNVKRVIVHRQYDPATF 1541
            |||||:..|:|:|||||:          |.|:.:   |..|..:|:......:...|..|...|.
Human    55 CGGVLVNERWVLTAAHCK----------MNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTH 109

  Fly  1542 ENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWGRLKYGG-GVPSVLQEVQVPIIEN 1605
            .|||.|::|:|..:..:.:..:.:|:. .:..|...||:|||...... ..||.|..|.|.:|..
Human   110 VNDLMLVKLNSQARLSSMVKKVRLPSR-CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISP 173

  Fly  1606 SVCQEMFHTAGHNKKIL-TSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHG-IKCA 1668
            ..|.:::      |.:| .|.||||..:.:|::|.||||||||.     |..|.|.||.| ..|.
Human   174 QDCTKVY------KDLLENSMLCAGIPDSKKNACNGDSGGPLVC-----RGTLQGLVSWGTFPCG 227

  Fly  1669 APYLPGVYMRTTFYKPWL 1686
            .|..||||.:...:..|:
Human   228 QPNDPGVYTQVCKFTKWI 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	78/244 (32%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	77/243 (32%)