DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and tpsab1

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	XP_002941509.1	Gene:	tpsab1 / 497002	XenbaseID:	XB-GENE-5892149	Length:	326	Species:	Xenopus tropicalis

Alignment Length:	278	Identity:	92/278 - (33%)
Similarity:	144/278 - (51%)	Gaps:	33/278 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1428 NLAFHSPSTE-----CGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITS 1487
            ||.|:..:.:     || :.:|.:.||.||..:|.|.:||||.|    ||.  .|..|||.|:::
Frog    14 NLGFYGCAADDAEPTCG-KSNVGTNRIAGGHEATKGEFPWQVAV----WLP--GKMFCGGTLLSN 71

  Fly  1488 RYVITAAHCQPGFLA-SLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELD 1551
            .:|:|:|.|..|..| |:|.::|...:||:.:.:.::.  .||:|:|..|..:.:..||||:||:
Frog    72 TWVLTSAQCLDGHNASSVVVILGSIKLSGNPKEETAIP--AKRIIIHPYYYFSNYSGDLALIELE 134

  Fly  1552 SPVQFDTHIVPICMPNDVADFT-GRMATVTGWGRLKYGG--GVPSVLQEVQVPIIENSVCQEMFH 1613
            .||.|.|:|.|:|:|.....|| |::..|.|||:.|:..  |:..||:..:|.:|.:.:||:.:
Frog   135 KPVDFTTYITPLCLPPPTVTFTPGQLCYVAGWGQKKFNDSEGISDVLRGAEVRLITSELCQDYY- 198

  Fly  1614 TAGHNKK---------ILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAA 1669
                |.|         |....:||...:|....|.||.||||.....:..| :.|..|..:.|..
Frog   199 ----NMKNDYNITGDVITNDTICARDIHGVHRICRGDGGGPLACPAGNSWY-VVGVASFVVLCGE 258

  Fly  1670 PYLPGVYMRTTFYKPWLR 1687
            ...||||....:|..|::
Frog   259 MGHPGVYTSVPYYMDWIQ 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	85/252 (34%)
tpsab1	XP_002941509.1	Tryp_SPc	38..275	CDD:214473	85/250 (34%)
tpsab1	XP_002941509.1	Tryp_SPc	39..277	CDD:238113	85/252 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	176	1.000	Domainoid score	I3546
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000