Protein Alignment flz and tmprss2

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_001008623.1
• Gene: tmprss2 / 494080
• ZFINID: ZDB-GENE-041212-48
• Length: 486
• Species: Danio rerio
• Alignment Length: 308
• Identity: 100/308 - (32%)
• Similarity: 148/308 - (48%)
• Gaps: 55/308 - (17%)

  Fly  1399 EIDQGATLSSYGGANGRKIHSTSRTLPTPNLAFHS----------PSTECGVRPHVKSGRIVGGK 1453
            ||....|.|.|.|            :.:|:|.|.|          ..|:||   .....|||||.
Zfish   207 EIGYKDTYSGYQG------------ILSPSLDFISACQSSTAVSLKCTDCG---RSTGNRIVGGT 256

  Fly  1454 GSTF-GAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHC-----QPGFLASLVAVMGEFD 1512
            ..|. |.:||||.:..|      .::.|||.:||..:::|||||     .||........:.:.:
Zfish   257 TVTSKGVWPWQVSLHYS------GRHLCGGSIITPYWILTAAHCVHQFSNPGGWTVYAGYLTQSE 315

  Fly  1513 I---SGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVADFTG 1574
            :   ||:         :|.|:::| .::|.|.|||:||:.|::.:...|:|.|:|:||....||.
Zfish   316 MASASGN---------SVNRIVIH-DFNPNTNENDIALMRLNTALTISTNIRPVCLPNKGMSFTA 370

  Fly  1575 RM-ATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSC 1638
            :. ..|||||.|..||...:.|||.::.:|::::|..   ...:|..|..:.:|||...|..|||
Zfish   371 QQDCYVTGWGALFSGGSSSATLQEAKIQLIDSTICNS---RPVYNGLITDTMICAGKLAGGVDSC 432

  Fly  1639 EGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWL 1686
            :|||||||| ......:.|.|..|.|..||....||||...|::..|:
Zfish   433 QGDSGGPLV-TNVRSLWWLLGDTSWGDGCAVRNKPGVYGNVTYFLDWI 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	86/248 (35%)
tmprss2	NP_001008623.1	DUF3824	<18..>77	CDD:372351
		LDLa	132..168	CDD:238060
		SRCR_2	173..248	CDD:470597	13/55 (24%)
		Tryp_SPc	252..482	CDD:238113	86/248 (35%)