DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and CG11313

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	101/366 - (27%)
Similarity:	160/366 - (43%)	Gaps:	62/366 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1357 KKPTRRVSSTVK-------TTTVSSARPADDE----------IVDEEDEEDVNPNPSDNEIDQGA 1404
            :.|.:|....|.       .:.::.:.|.|.|          :.|:.|...|...|   :.|...
  Fly    25 RNPNQRTGYCVNIPLCVPLNSVLAKSNPTDSEMRFIRESRCLVSDQSDLPFVCCTP---DTDYNT 86

  Fly  1405 TLSSYGGANGRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRES 1469
            |.:.   .|...||||  .||..::        ||  ..:...:|..|..:....:.|.||:...
  Fly    87 TRAR---PNDEVIHST--LLPDRSI--------CG--GDIAYNQITKGNETVLTEFAWMVLLEYR 136

  Fly  1470 TWLGLFTKNKCGGVLITSRYVITAAHC-------QPGFLASLVAV-MGEFDISGDLES------K 1520
            ...|...:..|.|.||.:|||:|||||       :.|.::..|:| :||.:.|..::.      .
  Fly   137 PHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLP 201

  Fly  1521 RSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVA---DFTGRMATVTGW 1582
            ..|...|:.:.:|..:....|.||:||:.|...|.:...|.|:|:|:.|.   ..:|:..||.||
  Fly   202 EPVQIAVEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGW 266

  Fly  1583 GRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKIL-TSFLCA-GYANGQKDSCEGDSGGP 1645
            ||.......| |..:::|..:|..:|:..:.:.    .:| .|.||| |.:.|  |||:||||||
  Fly   267 GRTLTSESSP-VKMKLRVTYVEPGLCRRKYASI----VVLGDSHLCAEGRSRG--DSCDGDSGGP 324

  Fly  1646 LVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWL 1686
            |:... :|.:.|.|.||.|:.|.:.:.|.||.....|:.|:
  Fly   325 LMAFH-EGVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWI 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	80/257 (31%)
CG11313	NP_651821.3	CLIP	24..78	CDD:288855	9/52 (17%)
		Tryp_SPc	116..367	CDD:238113	80/257 (31%)
		Tryp_SPc	116..364	CDD:214473	79/255 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457390
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840