DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and CG4613

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	124/356 - (34%)
Similarity:	173/356 - (48%)	Gaps:	58/356 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1358 KPTRRVSSTVKTTTVSSARPAD-------DEIVDEEDEEDV-------NPNPSDNEIDQGAT-LS 1407
            ||.|.....|..:|.||..|..       |::::...::.:       :..|||.....|:| ||
  Fly    38 KPERLPPLPVNGSTTSSTGPPPGVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLS 102

  Fly  1408 SY---------GGANGRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQ 1463
            |.         |||...:::..:             |..||| |:|  .|||||.......|||.
  Fly   103 SSASPVFPLEGGGAKAFRVNRCA-------------SCTCGV-PNV--NRIVGGTQVRTNKYPWI 151

  Fly  1464 VLVRESTWLGLFTKNKCGGVLITSRYVITAAHCQPGFLASLVAV-MGEFDISGDLESKRSVTKNV 1527
            ..:...|:|      .|||.||..|||:|||||..|.....|:| :.:.|.|   .:...||::|
  Fly   152 AQIIRGTFL------FCGGTLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRS---STHLGVTRSV 207

  Fly  1528 KRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMP-NDVADFTGRMATVTGWGRLKYGGGV 1591
            .....|..|||.:..:|:|||.||.|:.....:.|.|:| |.:.:|..:.|.|.|||..:.||..
  Fly   208 AFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAIVAGWGLSQEGGST 272

  Fly  1592 PSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYA-NGQKDSCEGDSGGPLVLQRPDGRY 1655
            .||||||.||||.|:.|:    ...:...|:.:.:||||. .|.:|:|:|||||||:::  |..:
  Fly   273 SSVLQEVVVPIITNAQCR----ATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVR--DRIF 331

  Fly  1656 ELAGTVSHGIKCAAPYLPGVYMRTTFYKPWL 1686
            .|||.||.|..||.|..||||.|.:.|..|:
  Fly   332 RLAGVVSFGYGCAKPDAPGVYTRVSRYLEWI 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	97/241 (40%)
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	97/240 (40%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	96/239 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457816
Domainoid	1	1.000	147	1.000	Domainoid score	I2768
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840