DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and CG6462

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	80/262 - (30%)
Similarity:	121/262 - (46%)	Gaps:	37/262 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly  1448 RIVGGKGSTFGAYPWQV-LVRESTWLGLFTKNKCGGVLITSRYVITAAHCQPGFLASLVAVMGEF 1511
            ||.||:.:|.|.:|:|| ||.:.:...|.   ||||.|||.::|:|||||....:|:.:......
  Fly    76 RIAGGELATRGMFPYQVGLVIQLSGADLV---KCGGSLITLQFVLTAAHCLTDAIAAKIYTGATV 137

  Fly  1512 --DISGDLESKRSVTKNVKRVIVHRQY----DPATF--ENDLALLELDSPVQFDTHIVPICMPND 1568
              |:...:|..:         :.||.:    |...|  .:||||:.|...|:....:.||.:..:
  Fly   138 FADVEDSVEELQ---------VTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGE 193

  Fly  1569 VAD---FTGRMATVTGWGRLKYGGGVPS---VLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLC 1627
            ...   ..|::.|::|||.|  |.....   :||.:...:|:...|...|.....:::   ..||
  Fly   194 FMHQNFLVGKVVTLSGWGYL--GDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQR---RHLC 253

  Fly  1628 AGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIK--CAAPYLPGVYMRTTFYKPWLRSIT 1690
            ...:|| :.:|.||||||:|....:..| |.|..|.|..  |.... |.||.|.|.|.||:|..|
  Fly   254 TDGSNG-RGACNGDSGGPVVYHWRNVSY-LIGVTSFGSAEGCEVGG-PTVYTRITAYLPWIRQQT 315

  Fly  1691 GV 1692
            .:
  Fly   316 AM 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	78/256 (30%)
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	77/254 (30%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	78/256 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940