DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and SPH93

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	108/414 - (26%)
Similarity:	174/414 - (42%)	Gaps:	80/414 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1343 VAAKVTTTTRRPATKKPTRRVSSTVKTTTVSSARPADDE---IVDEEDEEDVNPN---------- 1394
            :.|:::.|  |..|:.....:.|.||.....|.||.::|   ..:..:.....||
  Fly    79 INAQLSPT--RELTRDRPNTIESQVKEINDFSGRPTNNERNPATEPNNGGYTTPNGGYPVNNGGY 141

  Fly  1395 --------------PSDN----------EIDQGATLSSYGG--ANGRKIHSTSRTLPT-----PN 1428
                          ||:|          .::.|...::.||  ||.....:|:...||     |.
  Fly   142 PVNNGGYPSNNGGYPSNNGGYPVNNGGYPVNNGGYPANNGGYPANNGGYPTTNVGNPTNNGGNPT 206

  Fly  1429 LAFHSPSTECGVRP--HVKSGRIVG---GKGSTFG---------------AYPWQVLVRESTWLG 1473
            ..|.:| |..|..|  :|.|..::.   |..:..|               .|||.|.:..:   |
  Fly   207 TNFGNP-TNNGGNPTTNVGSSELLSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHN---G 267

  Fly  1474 LFTKNKCGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDP 1538
            .:.   .||.||....|:|.||........||...|::|:..|.|...|..:.|:|.::|..:|.
  Fly   268 QYL---AGGSLIQPNVVLTVAHRVITIETELVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDF 329

  Fly  1539 ATFENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWGRLKY-GGGVPSVLQEVQVPI 1602
            .:..|:||||.|:||.:.:.||..||:|.....|.||..||.|||:::| .....:||::||:.:
  Fly   330 KSGANNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLV 394

  Fly  1603 IENSVCQEMFHTA--GHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQ---RPDGRYELAGTVS 1662
            :..:||::...:.  |...::..:.:|||...| :|:|.||.|..|...   ...|.||.||.|:
  Fly   395 VNRNVCEKFLRSTRLGAKFELPKNIICAGGELG-RDTCTGDGGSALFCSIGGENSGVYEQAGIVN 458

  Fly  1663 HGIKCAAPYLPGVYMRTTFYKPWL 1686
            .|:.|....:|.:|...:.:..|:
  Fly   459 WGVGCGQEGIPAIYTEVSKFTNWI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	76/262 (29%)
SPH93	NP_609840.1	GRP	<136..189	CDD:254089	8/52 (15%)
		Tryp_SPc	250..485	CDD:238113	74/240 (31%)
		Tryp_SPc	252..482	CDD:214473	73/236 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457724
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840