DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and CG18478

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_609764.1	Gene:	CG18478 / 34923	FlyBaseID:	FBgn0028517	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	68/240 - (28%)
Similarity:	110/240 - (45%)	Gaps:	27/240 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1460 YPWQV-LVRESTWLGLFTKNKCGGVLITSRYVITAAH-CQPGFLASLVAVMGEFDISGDLESKRS 1522
            :||.: ::...:.:|       ||.|||...|:|||| .....:..:|...||::....||....
  Fly    55 FPWTIAVIHNRSLVG-------GGSLITPDIVLTAAHRIFNKDVEDIVVSAGEWEYGSALEKYPF 112

  Fly  1523 VTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWGRLK- 1586
            ....|.::::|:.::.....|:||||.||........|..||:|......:.....|.|||:.:
  Fly   113 EEAFVLKMVIHKSFNYQRGANNLALLFLDREFPLTYKINTICLPTQKRSLSSTRCIVAGWGKYQF 177

  Fly  1587 ----YGGGVPSVLQEVQVPIIENSVCQEMFHTA--GHNKKILTSFLCAGYANGQK--DSCEGDSG 1643
                |||    ||:::.:||:...:||:.....  |.|..:....:|||   |:|  |:|.||.|
  Fly   178 SDTHYGG----VLKKIDLPIVPRHICQDQLRKTRLGQNYTLPRGLICAG---GEKDNDACTGDGG 235

  Fly  1644 GPLV--LQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWL 1686
            |.|.  :.....::|..|.|:.|:.|....:|..|.....:|||:
  Fly   236 GALFCPMTEDPKQFEQIGIVNWGVGCKEKNVPATYTDVFEFKPWI 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	68/240 (28%)
CG18478	NP_609764.1	Tryp_SPc	50..283	CDD:238113	68/240 (28%)
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	67/238 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457714
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840