Protein Alignment flz and OVCH2

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: XP_047282834.1
• Gene: OVCH2 / 341277
• HGNCID: 29970
• Length: 569
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 95/291 - (32%)
• Similarity: 151/291 - (51%)
• Gaps: 43/291 - (14%)

  Fly  1421 SRTLPTPNLAFHSPSTECG-----VRP----HVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFT 1476
            |.||..|.    :||  ||     |:|    ::.| ||:||.....|:|||||.:::.      .
Human    26 SATLSLPK----APS--CGQSLVKVQPWNYFNIFS-RILGGSQVEKGSYPWQVSLKQR------Q 77

  Fly  1477 KNKCGGVLITSRYVITAAHC--QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYD-P 1538
            |:.|||.:::.::|||||||  ....:::|....||:|:|.....::::|  ::.||:|..:. .
Human    78 KHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLT--IETVIIHPHFSTK 140

  Fly  1539 ATFENDLALLELDSPVQFDTHIVPICMPNDVADF-TGRMATVTGWGRLKYGGGVPSVLQEVQVPI 1602
            ...:.|:|||::....||...:.|||:|.....| .|.:.|..|||||..||.:..|||||.:||
Human   141 KPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPI 205

  Fly  1603 IENSVCQEMFHTAGHNKKILT--SFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGI 1665
            :....|.....|.   |:.::  :|||.|:.:|.:|:|:|||||.|:.:...|.:.|||..|.|:
Human   206 LTWEECVAALLTL---KRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGL 267

  Fly  1666 KCAAPY----------LPGVYMRTTFYKPWL 1686
            .|...:          .||::...:...||:
Human   268 GCGRGWRNNVRKSDQGSPGIFTDISKVLPWI 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	83/254 (33%)
OVCH2	XP_047282834.1	Tryp_SPc	56..301	CDD:238113	83/254 (33%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001