Protein Alignment flz and HGFAC

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 86/281 - (30%)
• Similarity: 134/281 - (47%)
• Gaps: 38/281 - (13%)

  Fly  1423 TLPTPNLAFHSPSTE-CGVRPHVK----SGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGG 1482
            |||.|    .||..: || |.|.|    ..||:||..|..|::||...:    ::|   .:.|.|
Human   389 TLPEP----ASPGRQACG-RRHKKRTFLRPRIIGGSSSLPGSHPWLAAI----YIG---DSFCAG 441

  Fly  1483 VLITSRYVITAAHC----QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFEN 1543
            .|:.:.:|::||||    .|....|:|.....|:.:.|:.....:.|.:...: :..::|:  ::
Human   442 SLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTL-YSVFNPS--DH 503

  Fly  1544 DLALLEL----DSPVQFDTHIVPICMPNDVADF-TGRMATVTGWGRLKYG-GGVPSVLQEVQVPI 1602
            ||.|:.|    |........:.|||:|...:.| .|....:.|||.|... .|..|.|:|..||:
Human   504 DLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPL 568

  Fly  1603 IENSVCQ--EMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGI 1665
            :.:..|.  |::     ...|..:.|||||.:.:.|:|:|||||||..:: :|...|.|.:|.|.
Human   569 VADHKCSSPEVY-----GADISPNMLCAGYFDCKSDACQGDSGGPLACEK-NGVAYLYGIISWGD 627

  Fly  1666 KCAAPYLPGVYMRTTFYKPWL 1686
            .|...:.||||.|...|..|:
Human   628 GCGRLHKPGVYTRVANYVDWI 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	74/250 (30%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	74/250 (30%)