Protein Alignment flz and HABP2

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 98/293 - (33%)
• Similarity: 149/293 - (50%)
• Gaps: 52/293 - (17%)

  Fly  1421 SRTLPTPNL-AFHS-PSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWL------GLFTK 1477
            |.|.|:..| .|.| ..||...|   |..||.||..||.|.:|||..::.|..|      |.|
Human   287 SPTEPSTKLPGFDSCGKTEIAER---KIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHF-- 346

  Fly  1478 NKCGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYD----- 1537
              |||.||...:|:|||||.......|..|:|:.|:..:...::|.  .|:::..:..|:
Human   347 --CGGALIHPCWVLTAAHCTDIKTRHLKVVLGDQDLKKEEFHEQSF--RVEKIFKYSHYNERDEI 407

  Fly  1538 PATFENDLALLELDSPVQFDTH-------IVPICMPNDVADFTGRMATVTGWGRLKYGGGVPSVL 1595
            |   .||:|||:| .||  |.|       :..:|:| |.:..:|....::|||..:.|.|...:|
Human   408 P---HNDIALLKL-KPV--DGHCALESKYVKTVCLP-DGSFPSGSECHISGWGVTETGKGSRQLL 465

  Fly  1596 QEVQVPIIENSVC--QEMFHTAGHNKKILTSFLCAGYANGQK---DSCEGDSGGPLVLQRPDGRY 1655
             :.:|.:|.|::|  ::::     :..|..|.:|||  |.||   |:|:|||||||..:: ||.|
Human   466 -DAKVKLIANTLCNSRQLY-----DHMIDDSMICAG--NLQKPGQDTCQGDSGGPLTCEK-DGTY 521

  Fly  1656 ELAGTVSHGIKCAAPYLPGVYMRTTFYKPWLRS 1688
            .:.|.||.|::|..  .||||.:.|.:..|:::
Human   522 YVYGIVSWGLECGK--RPGVYTQVTKFLNWIKA 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	87/263 (33%)
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	87/263 (33%)