DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and F10

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	102/359 - (28%)
Similarity:	154/359 - (42%)	Gaps:	85/359 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1349 TTTRRPATKKPTRRVSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGATLSSYGGAN 1413
            :|...|..|....|...:|...|.:|          |.|.||:.|   |.:|
  Rat   166 STAPFPCGKTNKGRAKRSVALNTSNS----------EPDPEDLMP---DADI------------- 204

  Fly  1414 GRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSG---RIVGGKGSTFGAYPWQVLVRESTWLGLF 1475
               ::.|.    :|:...:...||    |...|.   |||||:....|..|||.|        ||
  Rat   205 ---LYPTE----SPSELLNLNKTE----PEANSDDVIRIVGGQECKRGECPWQAL--------LF 250

  Fly  1476 ----TKNKCGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISGDLESKR----SVTKNVKRVIV 1532
                |...|||.::...|::|||||........|.|       |||.:::    .:...|..:|.
  Rat   251 SDEETDGFCGGTILNEFYILTAAHCLHQAKRFKVRV-------GDLNTEQEDGGEMVHEVDMIIK 308

  Fly  1533 HRQYDPATFENDLALLELDSPVQFDTHIVPICMP-NDVAD---FTGRMATVTGWGRLKYGGGVPS 1593
            |.::...|::.|:|:|.|.:|:.|..::.|.|:| .|.|:   .|.:...|:|:||....|....
  Rat   309 HNKFQRDTYDFDIAMLRLKTPITFRENVAPACLPQKDWAEATLMTQKTGIVSGFGRTHEKGRQSK 373

  Fly  1594 VLQEVQVPIIENSVCQEMFHTAGHNKKILTSF------LCAGYANGQKDSCEGDSGGPLVLQRPD 1652
            ||:.::||.::.:.|           ::.|||      .||||...|:|:|:||||||.|.:..|
  Rat   374 VLKMMEVPYVDRNTC-----------RLSTSFSITQNMFCAGYDAKQEDACQGDSGGPHVTRFKD 427

  Fly  1653 GRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWL 1686
             .|.:.|.||.|..||.....|:|.:.|.:..|:
  Rat   428 -TYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWI 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	81/256 (32%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372
		Tryp_SPc	232..462	CDD:238113	81/256 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910