DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment flz and Tpsg1

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	XP_006524421.1	Gene:	Tpsg1 / 26945	MGIID:	1349391	Length:	368	Species:	Mus musculus

Alignment Length:	342	Identity:	110/342 - (32%)
Similarity:	164/342 - (47%)	Gaps:	52/342 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1362 RVSSTVKTTTVSSARPADDEIVDEEDEEDVN-----PNPSDNEIDQGATLSSYGGANGRKIHSTS 1421
            |:||    ..:|||:|:..  |.:::...::     ..|...|..|.||......|.|:...|.:
Mouse     8 RISS----EKLSSAQPSHQ--VTDKNGHWIHLCHGLQGPGLAESFQWATSKPTVSARGQYPDSLA 66

  Fly  1422 RTLPTPNLAFHSPSTECGVRPHVKS--GRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVL 1484
            .::        |..:.|| .|.|.:  .|||||..:..|.:|||..:|      |...:.|||.|
Mouse    67 NSV--------SSGSGCG-HPQVSNSGSRIVGGHAAPAGTWPWQASLR------LHKVHVCGGSL 116

  Fly  1485 ITSRYVITAAHCQPGFLASLVAVMGEFDIS-GDLESKRSVT-----KNVKRVIVHR-QYDPATFE 1542
            ::..:|:|||||..|.:.|     .::.:. |:|    :||     ..|||:|::. ...|....
Mouse   117 LSPEWVLTAAHCFSGSVNS-----SDYQVHLGEL----TVTLSPHFSTVKRIIMYTGSPGPPGSS 172

  Fly  1543 NDLALLELDSPVQFDTHIVPICMPNDVADF-TGRMATVTGWGRLKYGGGV--PSVLQEVQVPIIE 1604
            .|:||::|.|||...:.:.|:|:|...||| .|....|||||....|..:  |..|||.:|.:::
Mouse   173 GDIALVQLSSPVALSSQVQPVCLPEASADFYPGMQCWVTGWGYTGEGEPLKPPYNLQEAKVSVVD 237

  Fly  1605 NSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAA 1669
            ...|.:.:::. :...|....||   |.|..|:|:.|||||||.| ..|.::.||.||.|..|..
Mouse   238 VKTCSQAYNSP-NGSLIQPDMLC---ARGPGDACQDDSGGPLVCQ-VAGTWQQAGVVSWGEGCGR 297

  Fly  1670 PYLPGVYMRTTFYKPWL 1686
            |..||||.|.|.|..|:
Mouse   298 PDRPGVYARVTAYVNWI 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	88/248 (35%)
Tpsg1	XP_006524421.1	Tryp_SPc	87..317	CDD:238113	88/248 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842948
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840