Protein Alignment flz and KLK13

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 92/297 - (30%)
• Similarity: 133/297 - (44%)
• Gaps: 63/297 - (21%)

  Fly  1405 TLSSYGGAN--GRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVR 1467
            ||:..||.:  ..|:.:|:.|                      ||.:.||......:.|||.
Human    12 TLALSGGVSQESSKVLNTNGT----------------------SGFLPGGYTCFPHSQPWQA--- 51

  Fly  1468 ESTWLGLFTKNK--CGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISGDLESKRSVTKNVKRV 1530
                 .|..:.:  |||||:..::|:|||||   ....|...:|:..: |.:|:...| :.|...
Human    52 -----ALLVQGRLLCGGVLVHPKWVLTAAHC---LKEGLKVYLGKHAL-GRVEAGEQV-REVVHS 106

  Fly  1531 IVHRQY--DPA--TFENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWG-----RLK 1586
            |.|.:|  .|.  ..::|:.||||.||||...:|..:.:.::.....|....|:|||     ::.
Human   107 IPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVN 171

  Fly  1587 YGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRP 1651
            |    |..||...:.:..:..|::::     ..||..:.||||...|.|||||||||||||..|
Human   172 Y----PKTLQCANIQLRSDEECRQVY-----PGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNR- 226

  Fly  1652 DGRYELAGTVSHG-IKCAAPYLPGVYMRTTFYKPWLR 1687
                .|.|.||.| ..|..|..||||.|.:.|..|:|
Human   227 ----TLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIR 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	83/251 (33%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	83/249 (33%)