Protein Alignment flz and PRSS33

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_690851.2
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 103/291 - (35%)
• Similarity: 143/291 - (49%)
• Gaps: 46/291 - (15%)

  Fly  1411 GANGRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLF 1475
            |..|||                  |..|| :|.: |.|||||:....|.:|||..::..
Human    19 GTQGRK------------------SAACG-QPRM-SSRIVGGRDGRDGEWPWQASIQHR------ 57

  Fly  1476 TKNKCGGVLITSRYVITAAHCQPGFLASLVAVMGEFDIS-GDLE----SKRSVTKNVKRVIVHRQ 1535
            ..:.|||.||..::|:|||||.|     ..|:..|:.:. |.|.    |.|:::..|:||::...
Human    58 GAHVCGGSLIAPQWVLTAAHCFP-----RRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPD 117

  Fly  1536 YDPATFENDLALLELDSPVQFDTHIVPICMPNDVA-DFTGRMATVTGWGRLKYGGGVPS--VLQE 1597
            |.......|||||:|..||.....:.|:|:|...| ...|....|||||.|:.|..:|.  .||.
Human   118 YSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQG 182

  Fly  1598 VQVPIIENSVCQEMFHTAGH----NKKILTSFLCAGYANGQKDSCEGDSGGPLV-LQRPDGRYEL 1657
            |:||::::..|..::|....    .:.:|...|||||..|.||:|:|||||||. ||  .|.:.|
Human   183 VRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQ--SGSWVL 245

  Fly  1658 AGTVSHGIKCAAPYLPGVYMRTTFYKPWLRS 1688
            .|.||.|..||.|..||||.....|.||:::
Human   246 VGVVSWGKGCALPNRPGVYTSVATYSPWIQA 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	93/253 (37%)
PRSS33	NP_690851.2	Tryp_SPc	37..275	CDD:238113	93/250 (37%)