DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and F7

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_690059.1	Gene:	F7 / 260320	RGDID:	628678	Length:	446	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	118/400 - (29%)
Similarity:	174/400 - (43%)	Gaps:	85/400 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1361 RRVSSTVKTTTVSS-ARPADDEIVDEEDEEDVNPNP----------------SDNEIDQGAT--- 1405
            ||.:|.::....|| .|..::|....|:..::..:|                :.|....|.|
  Rat    40 RRANSLLEELWSSSLERECNEERCSFEEAREIFKSPERTKQFWTIYSDGDQCASNPCQNGGTCQD 104

  Fly  1406 -LSSY-----------------------GGANG------RKIHSTSRT-------LPTPNLAFHS 1433
             |.||                       ...||      |....|.||       :..|:.....
  Rat   105 HLKSYVCFCPLDFEGRNCEKNKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYVLQPDEVSCK 169

  Fly  1434 PSTE--CGVRPHVK-------SGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRY 1489
            |..|  ||..|.|:       .||||||.....|..|||.:::.:..|      .||.||:.:|:
  Rat   170 PKVEYPCGRIPVVEKRNFSRPQGRIVGGYVCPKGECPWQAVLKFNEAL------LCGAVLLDTRW 228

  Fly  1490 VITAAHC--QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDS 1552
            ::|||||  :.|.|.::..|:||.|.| :.|....| :.|::||:..:|.....::|:||:.|..
  Rat   229 IVTAAHCFDKFGKLVNITVVLGEHDFS-EKEGTEQV-RLVEQVIMPNKYTRGRTDHDIALVRLHR 291

  Fly  1553 PVQFDTHIVPICMP------NDVADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEM 1611
            ||.|..::||:|:|      |.:|..  |.:.|:|||:|...|.....|..::||.:....|.|.
  Rat   292 PVTFTDYVVPLCLPERAFSENTLASI--RFSRVSGWGQLLDRGATALELMVIEVPRLMTQDCLEH 354

  Fly  1612 FHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVY 1676
            ...:.:..:|..:..||||.:|.||:|:||||||..... .|.:.|.|.||.|..|||....|||
  Rat   355 AKHSANTPRITENMFCAGYMDGTKDACKGDSGGPHATHY-HGTWYLTGVVSWGEGCAAIGHIGVY 418

  Fly  1677 MRTTFYKPWL 1686
            .|.:.|..||
  Rat   419 TRVSQYIDWL 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	87/245 (36%)
F7	NP_690059.1	GLA	25..85	CDD:214503	9/44 (20%)
		EGF_CA	87..123	CDD:238011	6/35 (17%)
		Tryp_SPc	194..430	CDD:238113	87/245 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910