DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and mst1

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	277	Identity:	83/277 - (29%)
Similarity:	129/277 - (46%)	Gaps:	43/277 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1425 PTPNLAFHSPSTECGVR-PHVKSG-RIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITS 1487
            ||..:.|:    |||.| ..::|. |||||   |.|..||.|.:|:..     ..:.|||.|::|
Zfish   460 PTTEVEFN----ECGKREDRLRSRLRIVGG---TPGNSPWTVSLRDRK-----GNHFCGGSLVSS 512

  Fly  1488 RYVITAAHCQPGF---LASLVAVMGEF---DISGDLESKR-SVTKNVKRVIVHRQYDPATFENDL 1545
            .:||:...|....   |....|:||..   ...|:.:.:| |:||.|        ..|:  |:.|
Zfish   513 EWVISTKQCFSSCYVDLTGYTAMMGTLFRDPKEGEPDLQRISLTKIV--------CGPS--ESHL 567

  Fly  1546 ALLELDSPVQFDTHIVPICMPND---VADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSV 1607
            .:|:|::|.||:..:..||:|.:   |.|  |.:..:.|||..| |.|..:||...|:|::.|..
Zfish   568 VMLQLETPAQFNERVSQICLPPERYIVPD--GTICEIAGWGETK-GKGDETVLNVAQMPVLSNKD 629

  Fly  1608 CQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYL 1672
            |.:.|.......::.|....||..     :||.|.||||..|..| .:.|.|.:....:|.....
Zfish   630 CNQYFKGRVRENEMCTMAFQAGVG-----ACERDYGGPLACQNSD-CWVLEGVIIPMRRCGHAGQ 688

  Fly  1673 PGVYMRTTFYKPWLRSI 1689
            |.:::|.:.|..|::.:
Zfish   689 PNIFIRVSVYVDWIKKV 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	74/249 (30%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056
		Tryp_SPc	481..702	CDD:214473	74/247 (30%)
		Tryp_SPc	482..705	CDD:238113	74/249 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000