DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and TPSG1

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	XP_011520748.1	Gene:	TPSG1 / 25823	HGNCID:	14134	Length:	346	Species:	Homo sapiens

Alignment Length:	260	Identity:	100/260 - (38%)
Similarity:	137/260 - (52%)	Gaps:	29/260 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly  1438 CGVRPHVK--SGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHCQPGF 1500
            || ||.|.  .||||||..:..||:|||..:|      |...:.|||.|::.::|:|||||..|.
Human    51 CG-RPQVSDAGGRIVGGHAAPAGAWPWQASLR------LRRVHVCGGSLLSPQWVLTAAHCFSGS 108

  Fly  1501 LASLVAVMGEFDIS-GDLESKRSV-TKNVKRVIVHR--QYDPATFENDLALLELDSPVQFDTHIV 1561
            |.|     .::.:. |:||...|. ...|:::|:|.  ...|.| ..|:||:||..||...:.|:
Human   109 LNS-----SDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGT-SGDIALVELSVPVTLSSRIL 167

  Fly  1562 PICMPNDVADF-TGRMATVTGWGRLKYGGGVPS--VLQEVQVPIIENSVCQEMFHTAGHNKKIL- 1622
            |:|:|....|| .|....|||||..:.|..:|.  .|:||:|.:::...|:..:  .|....||
Human   168 PVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDY--PGPGGSILQ 230

  Fly  1623 TSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWLR 1687
            ...||   |.|..|:|:.|||||||.| .:|.:..|||||.|..|..|..||||.|...|..|:|
Human   231 PDMLC---ARGPGDACQDDSGGPLVCQ-VNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWIR 291

Fly 1688 1687
Human 292 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	93/247 (38%)
TPSG1	XP_011520748.1	Tryp_SPc	62..290	CDD:214473	92/245 (38%)
TPSG1	XP_011520748.1	Tryp_SPc	63..293	CDD:238113	93/247 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152876
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840