DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and Mst1

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	XP_038936729.1	Gene:	Mst1 / 24566	RGDID:	3114	Length:	747	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	71/262 - (27%)
Similarity:	113/262 - (43%)	Gaps:	34/262 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1437 ECGVRPHVKSG-RIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHC---- 1496
            :||.|....:. |:|||..   |..||.|.:|...     .::.|||.|:..::|:||..|
  Rat   507 KCGKRVDQSNRLRVVGGHP---GNSPWTVSLRNRQ-----GQHFCGGSLVKEQWVLTARQCIWSC 563

  Fly  1497 -QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQY-DPATFENDLALLELDSPVQFDTH 1559
             .|  |......:|..:     ::.:....|::||.|.:.. .||  .:.|.||:|:.||..:.|
  Rat   564 HDP--LTGYEVWLGTIN-----QNPQPGEANLQRVSVAKTVCGPA--GSQLVLLKLERPVILNHH 619

  Fly  1560 IVPICMPND--VADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKIL 1622
            :..||:|.:  |.. .|....:.|||..| |....:||...::.:|.:..|...:.......:|.
  Rat   620 VARICLPPEQYVVP-PGTNCEIAGWGESK-GTSNSTVLHVAKMKVISSQECNVKYRRRVQESEIC 682

  Fly  1623 TSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWLR 1687
            |..|.|     ...:||||.||||.....| .:.|.|.:.....||.|..|.::.|.:.:..|:.
  Rat   683 TEGLLA-----PTGACEGDYGGPLACYTHD-CWVLQGLIIPNRVCARPRWPAIFTRVSVFVDWIN 741

  Fly  1688 SI 1689
            .:
  Rat   742 KV 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	67/247 (27%)
Mst1	XP_038936729.1	PAN_1	32..111	CDD:394981
		KR	116..196	CDD:214527
		KR	199..276	CDD:214527
		KR	321..403	CDD:214527
		KR	408..490	CDD:214527
		Tryp_SPc	520..743	CDD:238113	67/247 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000