DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment flz and Tmprss11f

DIOPT Version :9

Sequence 1:NP_001137622.1 Gene:flz / 35902 FlyBaseID:FBgn0286782 Length:1693 Species:Drosophila melanogaster
Sequence 2:NP_848845.1 Gene:Tmprss11f / 243083 MGIID:2442348 Length:439 Species:Mus musculus


Alignment Length:289 Identity:94/289 - (32%)
Similarity:143/289 - (49%) Gaps:51/289 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly  1417 IHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTF-GAYPWQVLVRESTWLGLFTKNKC 1480
            |..:|..:|.|    .|.|||          |||.|:.:.. |.:|||..::   .:|  ..::|
Mouse   189 IRMSSSNIPLP----ASSSTE----------RIVQGRETAMEGEWPWQASLQ---LIG--AGHQC 234

  Fly  1481 GGVLITSRYVITAAHC-----QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPAT 1540
            |..||::.:::|||||     .|   ...:...|. .|:..|     |.::|.::|:|.:|...|
Mouse   235 GATLISNTWLLTAAHCFWKNRDP---TKWIVTFGT-TITPPL-----VKRSVGKIIIHEEYHRDT 290

  Fly  1541 FENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMAT-VTGWGRLKYGGGVPSVLQEVQVPIIE 1604
            .|||:||.:|.:.|:|...:..:|:|:.......:.:. |||:|.:...|...:.|::.:|..|.
Mouse   291 NENDIALAQLTTRVEFSNVVQRVCLPDSSMKLPPKTSVFVTGFGSIVDDGPTQNKLRQARVETIG 355

  Fly  1605 NSVCQEMFHTAGHNKK------ILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSH 1663
            :.||         |:|      |....||||:..|:.|:|:||||||||....|..| :.|.||.
Mouse   356 SDVC---------NRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNRDIWY-IVGIVSW 410

  Fly  1664 GIKCAAPYLPGVYMRTTFYKPWLRSITGV 1692
            |..||.|..||||.|.|.|:.|:.|.||:
Mouse   411 GQSCALPNKPGVYTRVTKYRDWIASKTGL 439

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
flzNP_001137622.1 PRK14948 <272..452 CDD:237862
PRK11633 <365..>439 CDD:236940
PRK10263 <547..>1005 CDD:236669
PHA03247 <792..1096 CDD:223021
Tryp_SPc 1449..1689 CDD:238113 82/252 (33%)
Tmprss11fNP_848845.1 SEA 60..164 CDD:396113
Tryp_SPc 207..436 CDD:238113 82/252 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4955
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

Return to query results.
Submit another query.