DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and Prss27

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_780649.1	Gene:	Prss27 / 213171	MGIID:	2450123	Length:	328	Species:	Mus musculus

Alignment Length:	289	Identity:	100/289 - (34%)
Similarity:	137/289 - (47%)	Gaps:	76/289 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1438 CGVRPHVKS-GRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHC----- 1496
            ||   |.|. .|:|||:.:..|.:||||.::.:   |:   :.|||.||...:|:|||||
Mouse    29 CG---HPKMFNRMVGGENALEGEWPWQVSIQRN---GI---HFCGGSLIAPTWVLTAAHCFSNTS 84

  Fly  1497 ---------------QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLA 1546
                           |||..|..|.                    ||:|..:.||.......|:|
Mouse    85 DISIYQVLLGALKLQQPGPHALYVP--------------------VKQVKSNPQYQGMASSADVA 129

  Fly  1547 LLELDSPVQFDTHIVPICMPNDVADF-TGRMATVTGWG------RLKYGGGVPSVLQEVQVPIIE 1604
            |:||..||.|..:|:|:|:|:....| :|....|||||      ||..    |.|||::.||||:
Mouse   130 LVELQGPVTFTNYILPVCLPDPSVIFESGMNCWVTGWGSPSEQDRLPN----PRVLQKLAVPIID 190

  Fly  1605 NSVCQEMFHTAGHNKKILTSF---------LCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGT 1660
            ...|..::     ||.:.:.|         ||||:|.|:||:|:||||||||. ..|..:..||.
Mouse   191 TPKCNLLY-----NKDVESDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVC-LVDQSWVQAGV 249

  Fly  1661 VSHGIKCAAPYLPGVYMRTTFYKPWLRSI 1689
            :|.|..||....||||:|.|.:..|:..|
Mouse   250 ISWGEGCARRNRPGVYIRVTSHHKWIHQI 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	94/275 (34%)
Prss27	NP_780649.1	Tryp_SPc	37..275	CDD:214473	94/273 (34%)
Prss27	NP_780649.1	Tryp_SPc	39..278	CDD:238113	94/274 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I3858
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910