Protein Alignment flz and PRSS55

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 100/331 - (30%)
• Similarity: 150/331 - (45%)
• Gaps: 49/331 - (14%)

  Fly  1389 EDVNPNPSDNEIDQGATLSSYG---GANGRKIHSTSRTLPTP----------------NLAFHSP 1434
            :.:|..|:|  :.:.|.|.|..   ...|.:|.:.....|:|                .|:|..|
Human    13 DKINHLPAD--VTRAAPLGSLSELLSRMGMRISTWKPAPPSPVPSSHWMLTKCFPFSFPLSFFPP 75

  Fly  1435 STECGVRP----HVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAH 1495
              |||.|.    ..:..||.||..:..|.:||||.::..      ::..|||.::...:::||||
Human    76 --ECGDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQAR------SEPFCGGSILNKWWILTAAH 132

  Fly  1496 C---QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFD 1557
            |   :..|...|..|:|    :.||.|.....|.|..:|:|:.:..|..:||:|||.|.||::.|
Human   133 CLYSEELFPEELSVVLG----TNDLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLD 193

  Fly  1558 THIVPICMPNDVADFTGRMATVTGWGRLKYG--GGVPSVLQEVQVPIIENSVCQEMFHTAGHNKK 1620
            ...||||:|......|.|...|.|||:....  ..|.:.|.:..:.|::...|.:||      .|
Human   194 DLKVPICLPTQPGPATWRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMF------PK 252

  Fly  1621 ILTSFLCAGYANGQKDSCEGDSGGPLV-LQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKP 1684
            :..:.|||||.|...|:|:|||||||| ...|..::...|.:|.|..|.....||:|.....|..
Human   253 LTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNL 317

  Fly  1685 WLRSIT 1690
            |:..:|
Human   318 WIEKVT 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	81/245 (33%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	81/245 (33%)