Protein Alignment flz and Tmprss2

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: XP_008766769.1
• Gene: Tmprss2 / 156435
• RGDID: 620766
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 507
• Identity: 135/507 - (26%)
• Similarity: 205/507 - (40%)
• Gaps: 120/507 - (23%)

  Fly  1270 GSNKTVATYQAGAGGTAKPVRVVTTRKPVR-TATTTRPKVTTKKPV----TRVTTKAPNKKTSAV 1329
            ||...:..|....|..::  .|.:.|.||. :.....|..:...||    .||||:|   .|.|:
  Rat     6 GSPPGIGPYYENHGYQSE--HVYSPRPPVSPSGYNLYPAQSCPSPVPQYAPRVTTQA---STPAI 65

  Fly  1330 STTTRKPATRRTT-------VAAKVTTTTRRPA-----------TKKPTRRVSSTVKTTTVSSAR 1376
            ....|...|..|:       ||..:.|.....|           :|..:..:......|.:||:.
  Rat    66 HIQPRSSGTLCTSKSKKSMLVALALGTVLAGAAVAAGLLWKFWDSKCSSSEMECGSSGTCISSSL 130

  Fly  1377 PAD--DEIVDEEDE----------------------------EDVNPNPSDNEI-DQGATLSSY- 1409
            ..|  .:..:.|||                            :|.|.:...... |.|...|.|
  Rat   131 WCDGVSQCPNGEDENRCVRLYGTSFTLQVYSSQRKAWYPVCQDDWNESYGRAACKDMGYKNSFYS 195

  Fly  1410 --------GGANGRKIHSTSRTLPTPNLAFHSPS-----------TECGVRPHVKSGRIVGGKGS 1455
                    |..:..|::.::..:......:||.|           .|||||...:..|||||..:
  Rat   196 SQGIPDQSGATSFMKLNVSAGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVRRQSRIVGGSTA 260

  Fly  1456 TFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHC------QPGFLASLVAVMGEFDIS 1514
            :.|.:||||.:...   |:   :.|||.:||..:::|||||      .|.:..:...::
  Rat   261 SPGDWPWQVSLHVQ---GI---HVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGIL------ 313

  Fly  1515 GDLESKRSV-----TKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPN-----DV 1569
                 |:|:     ...|::||.|..||..|..||:||::|.:|:.|:..:.|:|:||     |:
  Rat   314 -----KQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDVVKPVCLPNPGMMLDL 373

  Fly  1570 ADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQ 1634
            |    :...::|||.....|....||....||:||.|.|...:.   :|..|..:.:|||:..|.
  Rat   374 A----QECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYI---YNNLITPAMICAGFLQGS 431

  Fly  1635 KDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWL 1686
            .|||:||||||||..:.: .:.|.|..|.|..||..|.||||...|.:..|:
  Rat   432 VDSCQGDSGGPLVTLKNE-IWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWI 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	85/254 (33%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060	7/34 (21%)
		SRCR_2	152..247	CDD:464747	15/94 (16%)
		Tryp_SPc	254..485	CDD:238113	85/254 (33%)