DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and F9

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_032005.1	Gene:	F9 / 14071	MGIID:	88384	Length:	471	Species:	Mus musculus

Alignment Length:	346	Identity:	105/346 - (30%)
Similarity:	164/346 - (47%)	Gaps:	73/346 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1394 NPSDNEIDQGATLSSYGGANGRKIHSTSRTLPTP---------------------NLAFHSPSTE 1437
            |..||::....| ..|..|..:|  |...|:|.|                     |:.:.:.:..
Mouse   147 NSPDNKVICSCT-EGYQLAEDQK--SCEPTVPFPCGRASISYSSKKITRAETVFSNMDYENSTEA 208

  Fly  1438 CGVRPHVKSG-----------------RIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLI 1485
            ..::..:..|                 |:|||:.:..|..||||::...  :..|    |||.:|
Mouse   209 VFIQDDITDGAILNNVTESSESLNDFTRVVGGENAKPGQIPWQVILNGE--IEAF----CGGAII 267

  Fly  1486 TSRYVITAAHC-QPGFLASLVAVMGEFDI--SGDLESKRSVTKNVKRVIVHRQYDPAT---FEND 1544
            ..::::||||| :||....:||  ||::|  ..|.|.:|    ||.|.|.|.||: ||   :.:|
Mouse   268 NEKWIVTAAHCLKPGDKIEVVA--GEYNIDKKEDTEQRR----NVIRTIPHHQYN-ATINKYSHD 325

  Fly  1545 LALLELDSPVQFDTHIVPICMPNDVADFTG-----RMATVTGWGRLKYGGGVPSVLQEVQVPIIE 1604
            :||||||.|:..::::.|||:.|  .::|.     ....|:|||::...|...|:||.::||:::
Mouse   326 IALLELDKPLILNSYVTPICVAN--REYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVD 388

  Fly  1605 NSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAA 1669
            .:.|     .......|..:..||||..|.|||||||||||.|.: .:|...|.|.:|.|.:||.
Mouse   389 RATC-----LRSTTFTIYNNMFCAGYREGGKDSCEGDSGGPHVTE-VEGTSFLTGIISWGEECAM 447

  Fly  1670 PYLPGVYMRTTFYKPWLRSIT 1690
            ....|:|.:.:.|..|::..|
Mouse   448 KGKYGIYTKVSRYVNWIKEKT 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	90/250 (36%)
F9	NP_032005.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:291342	7/25 (28%)
		Tryp_SPc	236..464	CDD:214473	90/248 (36%)
		Tryp_SPc	237..467	CDD:238113	90/250 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910