DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and F7

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_034302.2	Gene:	F7 / 14068	MGIID:	109325	Length:	446	Species:	Mus musculus

Alignment Length:	273	Identity:	99/273 - (36%)
Similarity:	138/273 - (50%)	Gaps:	34/273 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1434 PSTE--CGVRPHV-------KSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRY 1489
            |..|  ||..|.|       :.||||||.....|..|||.:::.:   ||..   ||.||:.:|:
Mouse   170 PKVEYPCGRIPVVEKRNSSSRQGRIVGGNVCPKGECPWQAVLKIN---GLLL---CGAVLLDARW 228

  Fly  1490 VITAAHCQPG--FLASLVAVMGEFDIS---GDLESKRSVTKNVKRVIVHRQYDPATFENDLALLE 1549
            ::|||||...  :..::..||||.|.|   ||.:.:|     |.:||:..:|......:|:|||.
Mouse   229 IVTAAHCFDNIRYWGNITVVMGEHDFSEKDGDEQVRR-----VTQVIMPDKYIRGKINHDIALLR 288

  Fly  1550 LDSPVQFDTHIVPICMP------NDVADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVC 1608
            |..||.|..::||:|:|      |.:|..  |.:.|:|||:|...|.....|..::||.:....|
Mouse   289 LHRPVTFTDYVVPLCLPEKSFSENTLARI--RFSRVSGWGQLLDRGATALELMSIEVPRLMTQDC 351

  Fly  1609 QEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLP 1673
            .|....:.:..||..:..||||.:|.||:|:||||||..... .|.:.|.|.||.|..|||....
Mouse   352 LEHAKHSSNTPKITENMFCAGYMDGTKDACKGDSGGPHATHY-HGTWYLTGVVSWGEGCAAIGHI 415

  Fly  1674 GVYMRTTFYKPWL 1686
            |||.|.:.|..||
Mouse   416 GVYTRVSQYIDWL 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	91/249 (37%)
F7	NP_034302.2	GLA	24..85	CDD:214503
		EGF_CA	87..123	CDD:238011
		FXa_inhibition	132..168	CDD:291342
		Tryp_SPc	193..427	CDD:214473	90/247 (36%)
		Tryp_SPc	194..431	CDD:238113	91/249 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910