DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flz and F10

DIOPT Version :9

Sequence 1:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster
Sequence 2:	NP_001229297.1	Gene:	F10 / 14058	MGIID:	103107	Length:	493	Species:	Mus musculus

Alignment Length:	349	Identity:	96/349 - (27%)
Similarity:	152/349 - (43%)	Gaps:	66/349 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1349 TTTRRPATKKPTRRVSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGATLSSYGGAN 1413
            :|...|..|..|.|...:|...|..|....:|.::||:     ..:|::|.|:
Mouse   178 STAPFPCGKITTGRRKRSVALNTSDSELDLEDALLDED-----FLSPTENPIE------------ 225

  Fly  1414 GRKIHSTSRTLPTPNLAFHSPSTECGVRPHVKSGRIVGGKGSTFGAYPWQ-VLVRESTWLGLFTK 1477
               :.:.:.|.|.              |......|||||:....|..||| :|:.|.      .:
Mouse   226 ---LLNLNETQPE--------------RSSDDLVRIVGGRECKDGECPWQALLINED------NE 267

  Fly  1478 NKCGGVLITSRYVITAAHCQPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFE 1542
            ..|||.::...|::|||||........|.|   .|.:.:.|....:...|..||.|.::...|::
Mouse   268 GFCGGTILNEFYILTAAHCLHQARRFKVRV---GDRNTEKEEGNEMVHEVDVVIKHNKFQRDTYD 329

  Fly  1543 NDLALLELDSPVQFDTHIVPICMP-NDVAD---FTGRMATVTGWGRLKYGGGVPSVLQEVQVPII 1603
            .|:|:|.|.:|:.|..::.|.|:| .|.|:   .|.:...|:|:||....|...::|:.::||.:
Mouse   330 YDIAVLRLKTPITFRMNVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEKGRQSNILKMLEVPYV 394

  Fly  1604 ENSVCQEMFHTAGHNKKILTSF------LCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVS 1662
            :.:.|           |:.|||      .||||....:|:|:||||||.| .|....|.:.|.||
Mouse   395 DRNTC-----------KLSTSFSITQNMFCAGYEAKLEDACQGDSGGPHV-TRFKNTYYVTGIVS 447

  Fly  1663 HGIKCAAPYLPGVYMRTTFYKPWL 1686
            .|..||.....|:|.:.|.:..|:
Mouse   448 WGEGCARKGKYGIYTKVTTFLKWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	78/249 (31%)
F10	NP_001229297.1	GLA	36..97	CDD:214503
		EGF_CA	98..134	CDD:238011
		FXa_inhibition	141..176	CDD:291342
		Tryp_SPc	243..471	CDD:214473	78/248 (31%)
		Tryp_SPc	244..473	CDD:238113	78/249 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910