Protein Alignment flz and LOC1276790

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: XP_316180.5
• Gene: LOC1276790 / 1276790
• VectorBaseID: AGAMI1_013002
• Length: 896
• Species: Anopheles gambiae
• Alignment Length: 1214
• Identity: 248/1214 - (20%)
• Similarity: 402/1214 - (33%)
• Gaps: 426/1214 - (35%)

  Fly   548 SYNVVSQQ-TPSYGYPGAAVVQTEPAAQNPTFYQENESEKVQESDSQSDYGYTTTVNYESFYDKV 611
            ||::..|| ||.:| .|:.:::  |.|                  :.||.|   |::.:.|..:.
Mosquito    28 SYSIPQQQTTPVFG-SGSLLIR--PLA------------------TPSDRG---TIDGKHFTPRK 68

  Fly   612 SDEQDASAAV--SQSAEMPTARPGYGEDVSAVLEDHTMPANGY--------HDAEAPVAPQTSEF 666
            ...|..|...  .|||...|...|:|...:::..|..  ...|        |....|.||:
Mosquito    69 LQSQPRSQLFIPEQSAVPATGETGFGAPGTSIELDGI--DRSYRKVKKIVKHRRRYPAAPR---- 127

  Fly   667 NKMPVMGIAYPVDMSYMEEEGNLPATAAGYGQMSSDSYEASTESTY----QKLST-VQTEE---P 723
             ::......:|.....:......|.|..|    ..|.|.......|    :|... :||||   |
Mosquito   128 -RIKPGSAGWPHRKRRLNPHLFTPFTKWG----PCDYYCHQKRERYCIAKRKCGNHIQTEERICP 187

  Fly   724 Q----PTYVRPTTNANKQNRPVASYIGMVTMQHYNPQPGNGDYQAQVPPEVSVSSHTTKVQEQMD 784
            :    |.::.|....         :|.....:|::..|.|         :.::.:....||:|:.
Mosquito   188 KNICVPLHIPPIPTV---------HIEDTKEEHHSALPLN---------QFTIVNFDGHVQKQLQ 234

  Fly   785 ETSNGYQQSETTSGYVSPPTAVPAPAQRPQYDAVQGDASSERPVLVTASPRPRPKPSTKRPAVKR 849
            :  :|.::.:...               .|.|....|:.|:...::..||...|....|...:.:
Mosquito   235 Q--HGKKKKKKII---------------IQEDDELDDSDSDTDYVILKSPSKYPSFHRKEELLSQ 282

  Fly   850 PISGESTKKKPQPQPSAGAYNQEKISEHSTRKP-------VSNGYDKVPESPITHIQIKKPSATQ 907
            .|.|     ||.      ..|.:...:.....|       ..|||:..     :|..:|.|   :
Mosquito   283 MIKG-----KPL------LINLDDFDDKRILSPSLALAPHYDNGYETA-----SHKFVKYP---R 328

  Fly   908 HKEQEQTGY--PR--PASPAGYEQTTAAAPAPAAPSLNYD------------KPDAPPSQYDQPS 956
            |::|:|..|  ||  |:..:.|.:.            .||            |.:..|...||
Mosquito   329 HRQQQQQQYHLPRRQPSKLSDYFED------------YYDHLYRDGTGFSNRKGEEYPETDDQ-- 379

  Fly   957 APSASYDQLAPMPSLNYNEQHASSPGRKPSTAKPISTSYVTGPSTPRPPATVDYHYDNVPPLFMA 1021
                  :...|:..|:.:.:|...                         .|:.:.::.
Mosquito   380 ------EDWRPIVPLSNSSKHVGF-------------------------QTMMHRHEG------- 406

  Fly  1022 DDKLDAFIQSTAENIV--GSTPGNYQPPLVATASTPAYAHRPTSSGSYGHKKPGFVQINGTPKPP 1084
                |.| ..|.|.:|  .::...||..|:.:.||       .::|         |:...|.|
Mosquito   407 ----DTF-PHTTEKLVNDSNSTQRYQQQLLESFST-------ATTG---------VEEARTAK-- 448

  Fly  1085 RPTVLITPKPTAINLVTYSSLSDDSNKLASSTSSYVTGRPGVQGVSSNDFKDPG-YFGSSPVHVA 1148
                              ..:.|||...:||:             |..|.:..| ...|.|   |
Mosquito   449 ------------------REVDDDSTDTSSSS-------------SEQDEEQAGRMLKSGP---A 479

  Fly  1149 FTQ--STTEAVYAVPSDDKPAFPGYFGPTPSYPAFSVPGEKVGQNVMEETYTSPNDFVNFPPVRN 1211
            .||  :..:||:.:|                        .||     |..||..:.:.
Mosquito   480 LTQRRAREKAVFEMP------------------------RKV-----ENPYTKWSKWT------- 508

  Fly  1212 PNLNMSAASSAVTSDLD-LSTPAFVEDVVLKDKMHTLVHKLVASLQGNFEALADMIEEPGSNKTV 1275
                 ...:...|..|. ...|:|..:.|:::..:...       :|:|      .||...|:
Mosquito   509 -----KCTAKCTTRRLKRCRIPSFCGNDVIREIAYCYT-------EGSF------CEEWIGNQ-- 553

  Fly  1276 ATYQAGAGGTAKPVRVVTTRKPVRTATTTRPKVTTKKPVTRVTTKAPNKKTSAVSTTTRKPATRR 1340
             .||                                           |.:...:......|:|..
Mosquito   554 -LYQ-------------------------------------------NSRNIILPPPAAPPSTTT 574

  Fly  1341 TTVAAKVTTTTRRPATKKPTRRVSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPS----DNEID 1401
            ||.....||||..|...:|.|                               |:|:    .:.:.
Mosquito   575 TTTTTTTTTTTTTPRPSRPRR-------------------------------PHPNGLSRSDTVS 608

  Fly  1402 QGATLSSYGGANGRKIHSTSRTLPTPNLAFHSPSTECG---VRPHVKSG------RIVGGKGSTF 1457
            ..:|||:       :|.|..|.|..|.. ...|.| ||   ||...|..      ||:|||.|..
Mosquito   609 VPSTLSA-------QIFSNRRGLLQPEY-LPQPLT-CGLPMVRDKPKKNYLYNMLRIIGGKTSRR 664

  Fly  1458 GAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHCQPGFLASLVAVMGEFDI--SGDLESK 1520
            |.:||||.:     |..|.:..|||.|::||:::|||||   ....|...:||.::  |...|.:
Mosquito   665 GQWPWQVAI-----LNRFKEAFCGGTLVSSRWILTAAHC---VRKRLFVRLGEHNLQQSDGTEIE 721

  Fly  1521 RSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVADF-TGRMATVTGWGR 1584
            ..|..::|    |.:||..|.:||:|||:|...|:....|...|:|...... ||...|:.|||:
Mosquito   722 FRVELSIK----HPRYDKKTVDNDVALLKLPREVERSNFIGYSCLPERYQALPTGHTCTIIGWGK 782

  Fly  1585 LKYGGGV-PSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVL 1648
            .::.... ..:|.|.:|||:.|..|:.::    |:..|..:..|||:..|:.|:|.|||||||:.
Mosquito   783 KRHNDDAGTDILHEAEVPIVPNERCRAVY----HDYTITKNMFCAGHKRGRIDTCAGDSGGPLLC 843

  Fly  1649 Q---RPDGRYELAGTVSHGIKCAAPYLPGVYMRTTFYKPWLRSI 1689
            :   :.:..:.:.|..|.|..|......|:|.:...|..|:.|:
Mosquito   844 RDATKLNSPWTIYGITSFGDGCGKQNKFGIYTKVPNYVDWIWSV 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669	89/502 (18%)
		PHA03247	<792..1096	CDD:223021	52/328 (16%)
		Tryp_SPc	1449..1689	CDD:238113	80/246 (33%)
LOC1276790	XP_316180.5	None