Protein Alignment flz and LOC1276311

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: XP_315638.4
• Gene: LOC1276311 / 1276311
• VectorBaseID: AGAMI1_005289
• Length: 1321
• Species: Anopheles gambiae
• Alignment Length: 1521
• Identity: 319/1521 - (20%)
• Similarity: 501/1521 - (32%)
• Gaps: 517/1521 - (33%)

  Fly   437 PAQSTNNHHHNHLI--LDGGEFTHSDITHPGADADLVEDLQFSTGYGPQPVYAEPPKQ------- 492
            |..:.::.||.|::  :.|   .:|.:.|..|. |........|   .|..||:|.:|
Mosquito    34 PRTAPHSRHHVHMMPEMHG---AYSQVHHHRAQ-DPTPQQYIQT---DQYQYAQPQRQHPSLVGP 91

  Fly   493 QQQQQPAEQSYISSSTSAKRPTTGHNSPTTVSSITTHVDSIESIILQLNNTSHGPSYNVVSQQTP 557
            |||||..:|                                           ||||       .|
Mosquito    92 QQQQQQQQQ-------------------------------------------HGPS-------GP 106

  Fly   558 SYGYPGAAVVQTEPAAQNPTFYQENESEKVQESDSQSDYGYTTTVNYESFYDKVSDEQDASAAVS 622
            .| .||.      |.|..||           |:.....||                  .:.|...
Mosquito   107 QY-QPGV------PLAPYPT-----------ETQRSPAYG------------------RSQAYTQ 135

  Fly   623 QSAEMPTA-RPGYGEDVSAVLEDHTMPA------------NGYHDAEAP---------------- 658
            |.|.:|.| |.||||:...:.|  |.||            ..::..|.|
Mosquito   136 QPAPVPLAPRFGYGEEDRLIGE--TAPAAKLIRQPVHTLLKDFNGLECPEGRTGHFPYVMDCRQF 198

  Fly   659 ------------VAPQT------------SEFNKMPVMGIAYPVDMSYMEEEGNLPATAAGYGQM 699
                        .||.|            |:.:.:||     |...|..|.....|...|.|
Mosquito   199 LSCWKGRGFILNCAPGTLFNPNTRECDHPSKVSCLPV-----PSLNSVNEPANRAPPKLASY--- 255

  Fly   700 SSDSYEASTESTYQKLSTVQTEEPQPTYVRPTTNANKQNRPVA--SYIGMVTMQHYNPQP----- 757
                      :..::....|.::.||.|::|..:..:|.....  ..||:      .|.|
Mosquito   256 ----------TDQRQPQQFQQQQRQPQYLQPQQSLRQQEELTCPPGVIGL------RPHPTDCRK 304

  Fly   758 ----GNGDYQAQ-------VPPEVSVSSHTTKVQEQMDETSN---GYQQ-------SETTSGYVS 801
                .||....|       ..|.:....|...|  ..|::.|   .|.:       |..||.|.
Mosquito   305 FLNCNNGARFVQDCGPGTAFNPLILTCDHLRNV--DCDKSENVIVDYDRPTSRPVASGPTSHYY- 366

  Fly   802 PPTAVPAPAQRPQYDAVQGDASSERPVLVTASPRPRPKPSTKRPAV---KRPISGESTKKKPQPQ 863
             |:.:||.:|  ...||.......||.:    |.|:.:...::|:.   :.|...:..:..|..|
Mosquito   367 -PSHIPAGSQ--LVPAVVNPHQQSRPTI----PAPQQQTPPRQPSATGDRAPAHPDVEQIDPDHQ 424

  Fly   864 PSAGAYNQE--KISEHSTRKPVSNGYD-----KVPESPITHIQIKKPSATQHKEQEQTGYPRPAS 921
            |:...::::  :..:....:||.:|:|     ..||    .:..::|.|::
Mosquito   425 PTESNFDEDYGEQPDADGEEPVYDGFDLRSNFGAPE----QVDRRRPKASR-------------- 471

  Fly   922 PAGYEQTTAAAPAPA--------APSLNYDKPDAPPSQYDQPSAPSASYDQLAPMPSLNYNEQHA 978
               .:.||.|.|.|.        ..||:.| ||...| ..:|...:...:|..|:|:
Mosquito   472 ---TQATTTAKPYPVYIRPPSRQPESLHRD-PDVVQS-VQRPVYVALPLEQTTPVPT-------- 523

  Fly   979 SSPGRKPSTAKPISTSYVTGPSTPRPPATVDYHYDNVPPL---FMADDKLDAFIQST--AENIVG 1038
                  .:|::|:.|.:   |:..:....:..|.|.:..:   :|.:.|....:.:|  :..:..
Mosquito   524 ------STTSRPLRTPF---PTVRKEDIEIQQHLDALKLMLTPYMKEHKDTVALNTTKLSTMMTT 579

  Fly  1039 STPGNYQPPLVATASTPAYAHRPTSSGSYGHKKPGFVQINGTPKPPRPTVLITPKPTAINLVTYS 1103
            :|.....||:|.....||    ||...:|   ||       :.....|.||  |:.:.:|...|.
Mosquito   580 TTTTTEPPPIVQVIGLPA----PTPRNNY---KP-------SSAAAAPYVL--PRASEVNDFFYG 628

  Fly  1104 SLSDDSNKLAS--STSSYVTGRPGVQGVSSNDFKDPGYFGSSPVHVAFTQSTTEAVYAVPSDDKP 1166
              :.:...|||  ....|:| .| |:|.:..:.:...|    |::...|.:||....|.|: ..|
Mosquito   629 --ASEPVPLASWPLPPPYIT-EP-VEGPAKKEPESVVY----PIYRRTTPTTTTTTTASPA-PAP 684

  Fly  1167 AFPGYFGPT-PSYPAFSVPGEKVGQNVMEETYTSPNDFVNFPPVRNPNLNMSAASSAVTSDLDLS 1230
            |....||.. ||:....||.   .......|.|.|....:..| |:|........:.|..|
Mosquito   685 AISSRFGDNRPSWRPLIVPH---ATTTKTPTTTPPATTTSTTP-RDPCYGKFNCGNGVCID---- 741

  Fly  1231 TPAFV-----------EDVVLKDKMHTLVHKLVASLQGNFEALA----DMIEEPGSNKTVATYQA 1280
             .|.|           ::.|.....:.|  ||....||:.|...    ..:.:.|     .|.:|
Mosquito   742 -EAEVCDGRDGCGNRADEQVCDHIGYEL--KLSKKAQGSVEVRVYDRWGYVCDDG-----FTLEA 798

  Fly  1281 G---------AGGTAKPVRVVTTRKPVRTATTTRPKVTTKKPVTRVTTKAPNKKTSAVSTTTRKP 1336
            |         |||..:          :::.:...|..|  .|........|.....||.....:.
Mosquito   799 GNVVCRELGFAGGAIE----------IKSHSYFPPNGT--DPDEPEQQYGPFFMMDAVRCQGNES 851

  Fly  1337 ATRRTTVAAKVTTTTRRPATKKPTRRVSSTVKTTTVSSARPAD-----------------DEIVD 1384
            :.|..:......:...|       ..|...|..|.|.|. |.|                 |.:.|
Mosquito   852 SLRECSFNGWGVSDCNR-------EEVVGVVCRTPVMSC-PQDYWLCHASEECIPVQFLCDNVRD 908

  Fly  1385 EEDEEDVNPN-------------PSDNE--------------------IDQGATLSSYGGANG-- 1414
            ..|..|.:|:             |:|.|                    :.:...:....|.||
Mosquito   909 CADGSDESPDHCKAPLAVRLVAGPTDREGRVEINYHGTWGTVCDDDFGVREARVICRQLGFNGTA 973

  Fly  1415 --RKI---------------------------------HSTSRT----------LPT-------- 1426
              ||.                                 |:...|          :||
Mosquito   974 EVRKSVYPPGVGQIWLDQVACNGTEPSIEDCVHWHWGEHNCGHTEDVGVRCGVYVPTKARAARLR 1038

  Fly  1427 ---PNLAFH--------SPSTECG-------VRPHVKSGRIVGGKGSTFGAYPWQVLVREST--W 1471
               ||..|.        .|.| ||       :|......|:|.|..:.:|.:|||..:|..|  |
Mosquito  1039 ATRPNPRFDFVERSRKIHPDT-CGRVLIDPTLRKPTYGARVVHGSETVYGHHPWQASLRVKTMHW 1102

  Fly  1472 LGLFTKNKCGGVLITSRYVITAAHCQPGFLASLVAV-MGEFDISGDLESKRSVTKNVKRVIVHRQ 1535
                    ||.||||..:|:|||||..|:..|...| :|::..:....::..:.  ::...:|.|
Mosquito  1103 --------CGAVLITRYHVLTAAHCLIGYPKSTYRVRIGDYHTAAYDNAELDIF--IENTYIHEQ 1157

  Fly  1536 Y-DPATFENDLALLELDSPVQFDTHIVPICMP-NDVADFTGRMATVTGWGRLKYGGGVPSV-LQE 1597
            : :.....||:|::.|.:||:|:.::.|||:| .|.....|:..|::|||..:.|....|. |:.
Mosquito  1158 FREGHHMSNDIAVVVLKTPVRFNDYVQPICLPARDAPYLPGQNCTISGWGATEAGSKDSSYDLRA 1222

  Fly  1598 VQVPIIENSVCQ--EMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGT 1660
            ..||::.:|||:  |::     ...::....|||......|||:||||||||....:|.:.|.|.
Mosquito  1223 GTVPLLPDSVCRRPEVY-----GDSLIDGMFCAGTLEPGVDSCDGDSGGPLVCPNSEGLHTLTGI 1282

  Fly  1661 VSHGIKCAAPYLPGVYMRTTFYKPWL 1686
            ||.|..|.....||||::...|:.|:
Mosquito  1283 VSWGKHCGYANKPGVYLKVAHYRDWI 1308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940	1/1 (100%)
		PRK10263	<547..>1005	CDD:236669	106/556 (19%)
		PHA03247	<792..1096	CDD:223021	66/333 (20%)
		Tryp_SPc	1449..1689	CDD:238113	80/246 (33%)
LOC1276311	XP_315638.4	None