Protein Alignment flz and Cfd

DIOPT Version :10

• Sequence 1: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 257
• Identity: 74/257 - (28%)
• Similarity: 124/257 - (48%)
• Gaps: 25/257 - (9%)

  Fly  1438 CGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHCQPGFL- 1501
            |..:|.   |||:||:.:...|.|:...|:.:      ..:.|||.|:..::|::||||..|..
Mouse    18 CAAQPR---GRILGGQEAAAHARPYMASVQVN------GTHVCGGTLLDEQWVLSAAHCMDGVTD 73

  Fly  1502 -ASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHIVPICM 1565
             .|:..::|...:|.....||  ..:|:.|:.|....|.:.|:||.|.:|........|:.|:.:
Mouse    74 DDSVQVLLGAHSLSAPEPYKR--WYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPL 136

  Fly  1566 P-NDVADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAG 1629
            . .|.....|.:..|.|||.:.:.|..|.||.:::|.|:..:.|....:   |:..:..:.:||
Mouse   137 QYEDKEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTY---HDGVVTINMMCA- 197

  Fly  1630 YANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIK-CAAPYLPGVYMRTTFYKPWLRSIT 1690
             .:.::|:|.||||.|||...     .:.|.|:.|.: |.....||||.|.:.|:.|:.:||
Mouse   198 -ESNRRDTCRGDSGSPLVCGD-----AVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENIT 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	68/243 (28%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	68/243 (28%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)